不同强度跑台运动对大鼠胫骨软骨下骨三维结构影响.docVIP

不同强度跑台运动对大鼠胫骨软骨下骨三维结构的影响 　　【摘要】 目的 分析不同??度跑台运动对大鼠胫骨软骨下骨三维结构的影响。方法 选取120只清洁级大鼠作为研究对象， 参照啮齿类动物饲养国家标准， 喂食1周后， 运用随机分组方法将其分为对照组和观察组， 每组60只。经过3 d的适应性运动训练后， 对照组给予低强度跑台运动训练， 观察组给予高强度跑台运动训练。观察两组大鼠胫骨软骨下骨松质骨结构、下骨板结构。结果 对照组大鼠松质骨分离度（0.138±0.024）mm显著低于观察组大鼠（0.176±0.010）mm， 对照组大鼠松质骨厚度（0.158±0.037）mm显著大于观察组大鼠（0.121±0.013）mm， 差异有统计学意义（Plt;0.05）。观察组大鼠下骨板孔隙率显著低于对照组， 而下骨板骨密度、厚度均高于对照组， 差异均有统计学意义（Plt;0.05）。 　　结论 跑台运动强度与大鼠胫骨软骨下骨三维结构具有明显的影响， 与低强度跑台运动相比， 高强度跑台运动对大鼠胫骨软骨下骨三维结构的影响更加明显。 　　【关键词】 跑台运动;大鼠;胫骨软骨下骨;三维结构 　　DOI：10.14163/j.cnki.11-5547/r.2018.07.115 　　【Abstract】 Objective To analyze the effect of treadmill exercise at different intensities on the three-dimensional structure of tibial subchondral bone in rats. Methods A total of 120 clean-grade rats as study subjects were fed for 1 week according to the rodent feeding national standard， and they were divided by random grouping method into control group and observation group， with 60 rats in each group. After 3 d of adaptive exercise training， the control group received low intensity treadmill exercise training. The observation group received high intensity treadmill exercise training. The tibial subchondral cancellous bone structure and inferior bone plate structure of the two groups were observed. Results The control group had obviously lower cancellous bone separation as （0.138±0.024） mm than （0.176±0.010） mm in the observation group， and the control group had obviously larger cancellous bone thickness as （0.158±0.037） mm than （0.121±0.013） mm in the observation group. Their difference was statistically significant （Plt;0.05）. The observation group had obviously lower porosity of the lower bone plate than the control group， and higher bone density and thickness of the lower bone plate than the control group. Their difference was statistically significant （Plt;0.05）. Conclusion There was obvious effect of treadmill exercise intensity on three-dimensional structure of tibial subchondral bone in rats. Compared with low intensity tre