不同剂量右美托咪定辅助用药对快通道全麻苏醒期影响.docVIP

不同剂量右美托咪定辅助用药对快通道全麻苏醒期的影响 　　【摘要】 目的：观察不同剂量右美托咪定辅助用药对快通道全麻苏醒期的影响。方法：选择全麻患者90例，按入院时间随机分成A、B、C三组，三组分别以1、0.5、0.2 μg/kg于麻醉前15 min静脉输注右美托咪定，后行全凭静脉麻醉。记录全麻期间各时间点血流动力学变化及苏醒期自主呼吸恢复时间、呼唤睁眼时间、拔管时间及并发症发生情况。结果：三组苏醒时间无差异（P0.05），A组在麻醉诱导前心率下降明显，苏醒期舌后坠，SPO2较低，C组苏醒期躁动发生率比B组高，比较差异均有统计学意义（P0.05）。结论：0.5μg/kg右美托咪定辅助麻醉，血流动力学更稳定，对麻醉苏醒无影响且苏醒质量更高。 　　【关键词】 右美托咪定； 快通道麻醉； 苏醒期 　　中图分类号 R614 文献标识码 B 文章编号 1674-6805（2014）29-0030-03 　　Effects of Different Doses Dexmedetomidine in Fast Track Anesthesia on the Recovery of Patients after General Anesthesia/LI Zi-hu，YE Qiang.//Chinese and Foreign Medical Research，2014，12（29）：30-32 　　【Abstract】 Objective：To observe the effects of different doses dexmedtomidine of fast track anesthesia in the recovery of patients after general anesthesia.Method：90 cases of patients accepted general anesthesia，were randomly divide into 3 groups（group A、group B、group C），3 groups patients received dexmedetomidine 1，0.5，0.2μg/kg lasting for 15 min before general anesthesia，after total intravenous anesthesia，each time point during general anesthesia hemodynamic changes and the times of spontaneous breathing recovery，opening of eyes，extubation and side-effect were recorded.Result：There was no significant difference in waking time in the 3 groups （P0.05）.The patients of group A had significantly decreased heart rate before induction of anesthesia and lower SpO2 on the recovery（P0.05）.The incidence agitation in group C was higher than the group B（P0.05）.Conclusion：Supplemental anesthesia with 0.5 μg/kg dexmedetomidine has a more stable hemodynamics， and a higher postoperative recovery quality，it does not affects the patients’ awaken period also. 　　【Key words】 Dexmedetomidine； Fast track anesthesia； Awaken period 　　First-author’s address： Kanghua Hospital of Dongguan City， Dongguan 523000，China 　　随着医疗技术的进步与发展，人们对麻醉提出了更高的要求，于是，快通道麻醉的理念被提出。快通道麻醉指患者在术后绕过第一阶段恢复即麻醉后监护室，直接进入二级病房的过程，增加手术周转，降低患者费用[1]。快通道麻醉既要维持足够的麻醉深度，保证血流动力学稳定，又要求术后意识、肌张力等快速恢复，实现早期拔出气管导管。丙泊酚与瑞芬太尼的黄金组合出现，是较理想的快通道全身麻