主动脉内球囊反搏后发生血小板减少症危险因素及对近期预后影响临床分析.docVIP

主动脉内球囊反搏后发生血小板减少症的危险因素及对近期预后影响的临床分析 　　[摘要]目的 分析及探讨临床应用主动脉内球囊反搏后发生血小板减少症的危险因素及对近期预后的影响。方法 选取我院2014年3月～2016年3月的108例接受主动脉内球囊反搏治疗患者，根据是否发生血小板减少症分为血小板减少组（74例）及非血小板减少组（34例），回顾性分析入选患者的血小板情况及临床特点。结果 74例患者（68.5%，74/108）发生血小板减少症，血小板减少程度随球囊反搏时间延长而加重。多因素Logistic回归分析显示，基线血小板计数是本研究中唯一具有统计学差异的影响因素（P0.05）。结论 血小板减少症的程度与球囊反搏应用时间相关，较低的基线血小板计数是发生血小板减少症的独立危险因素，血小板减少症不影响疾病的近期预后。 　　[关键词]主动脉内球囊反搏；血小板减少症；危险因素；预后 　　[中图分类号] R543.1 [文献标识码] A [文章编号] 1674-4721（2018）3（a）-0017-04 　　Clinical analysis of the risk factors and short-term prognosis of thrombocytopenia among patients undergoing intra-aortic balloon pump counterpulsation 　　LUO Jie-hong LIU Jin-guang SHEN Yuan-sheng 　　Department of Cardiology，Huizhou Municipal Central Hospital in Guangdong Province，Huizhou 516001，China 　　[Abstract]Objective To analyze and explore the risk factors of thrombocytopenia and its influence on the short-term prognosis in patients undergoing intra-aortic balloon pump （IABP） counterpulsation.Methods 108 patients who received IABP in our hospital from March 2014 to March 2016 were selected and divided into the thrombocytopenia group （74 cases） and the non thrombocytopenia group （34 cases） according to whether thrombocytopenia occurred.The platelet and clinical features of the selected patients were analyzed retrospectively.Results Thrombocytopenia occurred in 74 patients （68.5%，74/108），and the degree of thrombocytopenia increased with the duration of IABP support.Multi factor Logistic regression analysis showed that baseline platelet count was the only influential factor in this study （P0.05）.Conclusion The degree of thrombocytopenia is related to the duration of IABP support.Lower baseline platelet count is independent risk factor for thrombocytopenia，which is not affect the short-term prognosis. 　　[Key words]Intra-aortic balloon pump；Thrombocytopenia；Risk factors；Prognosis 　　主动脉内球囊反搏泵（intra-aortic balloon pump，IABP）自1968年首次报道应用于救治急性心肌梗死合并心源性休克的患者以来，已经在心血管危重患者的抢救中发挥了非常重要的作用，现广泛应用于心源性休克、高危经皮冠状动脉介入治疗、缺血相关的