乳腺癌保乳术后调强放疗与常规放疗参数对比分析.docVIP

乳腺癌保乳术后调强放疗与常规放疗参数的对比分析 　　[摘要] 目的 分析对比乳腺癌保乳术后调强放疗与常规放疗的参数。方法 该次研究选取该院收治的90例乳腺癌患者，随机分两组。对照组45例选择常规放疗，观察组45例选择调强放疗。分析对比两组乳腺癌患者的剂量分布均匀指数、计划靶区剂量体积比、肺脏剂量体积比。结果 观察组乳腺癌患者的剂量分布均匀指数为（1.07±0.01），对照组乳腺癌患者的剂量分布均匀指数为（1.53±0.73）。观察组乳腺癌患者的计划靶区剂量体积比、肺脏剂量体积均优于对照组（P0.05）。结论 对于乳腺癌患者来说，选择调强放疗不但能够使得放射野内的剂量均匀分布，而且还能显著降低计划靶区的剂量体积比，减少肺脏的照射剂量。 　　[关键词] 乳腺癌保乳术；调强放疗；常规放疗 　　[中图分类号] R730 [文献标识码] A [文章编号] 1674-0742（2016）04（c）-0054-02 　　[Abstract] Objective To analyze and compare the parameters of intensity modulated radiation therapy and conventional fractionation radiation therapy after breast conservative surgery for breast cancer. Methods 90 cases of patients with breast cancer treated in our hospital from December 2012 to December 2014 were selected and randomly divided into two groups with 45 cases in each， the control group selected the conventional fractionation radiation therapy， the observation group selected the intensity modulated radiation therapy， the dose profile uniformity index， planning target dose-volume ratio and lung dose-volume ratio of the two groups were analyzed and compared. Results The dose profile uniformity index was （1.07±0.01） in the observation group and （1.53±0.73） in the control group， and the planning target dose-volume ratio and lung dose-volume in the observation group were better than those in the control group（P0.05）. Conclusion For patients with breast cancer， the choice of intensity modulated radiation therapy can not only make the distribution of dose in the radiation field uniformity， but also obviously reduce the dose-volume ratio in the planning target region and reduce the radiation dose of lung. 　　[Key words] Breast conservative surgery for breast cancer； Intensity modulated radiation therapy； Conventional fractionation radiation therapy 　　据相关数据显示，我国乳腺癌患者的数量在不断增多[1]。如不及时给予患者有效的临床治疗，将给患者的身心健康乃至生命安全造成极其不利的影响。为了研究出乳腺癌患者的最佳放疗方案，特选取该院2012年12月―2014年12间收治的90例乳腺癌患者，随机分2组。对照组45例选择常规放疗，观察组45例选择调强放疗，经研究证实，对于乳腺癌患者来说，选择调强放疗不但能够使得放射野内的剂量均匀分布，而且还能显著降低计划靶区的剂量体