中药在异位妊娠保守治疗中疗效观察.docVIP

中药在异位妊娠保守治疗中的疗效观察 　　[摘要] 目的:观察用中药联合甲氨蝶呤(MTX)及米非司酮治疗异位妊娠的效果。方法:A组,MTX单次肌注并口服米非司酮及中药,B组,MTX单次肌注并仅口服米非司酮,比较两组的治疗效果。结果:A组治愈率为 95.9%,B组为54.1%;A组与B组比较,血β-HCG降至正常所需的时间明显缩短,包块缩小快,再次宫内妊娠率高,两组间差异有统计学意义(P0.05)。结论:在传统的MTX等药物保守治疗异位妊娠中加服中药可促进疗效,提高再次宫腔妊娠率,减少MTX的重复用量而减轻药物毒副作用,值得推广。 　　[关键词] 异位妊娠;甲氨蝶呤;米非司酮;中药 　　[中图分类号] R714.220 [文献标识码] A[文章编号] 1673-7210(2010)02(b)-088-02 　　 　　Observation on the curative effect of traditional Chinese medicine in the conservative treatment for ectopic pregnancy 　　CHEN Wenhui 　　(The Peoples Hospital of Maoming, Maoming 525000, China) 　　[Abstract] Objective: To observe the effect of traditional Chinese medicine combining with methotrexate (MTX) and mifepristone in the treatment of ectopic pregnancy. Methods: Group A, single intramuscular injection of MTX and oral intake of mifepristone and traditional Chinese medicine; Group B, single intramuscular injection of MTX and only oral intake of mifepristone. The curative effects of two groups were compared.Results: The cure rate of group A was 95.9% andgroup B was 54.1%. The time needed by the drop of blood β-HCG to the normal value in group A was obviously shorter than that in group B and the reduction of block was more quickly and rate of reintrauterine-pregnancy was higher in group A comparing with group B. The differences in the two groups had statistic significance (P0.05). Conclusion: It could facilitate the curative effect, improve the rate of again intrauterine pregnancy and reduce the drug by-reaction of repeated use of MTX that the traditional Chinese medicine is added besides the traditional MTX drug conservative treatment for ectopic pregnancy, which is valuable for popularization. 　　[Key words] Ectopic pregnancy; Methotrexate; Mifepristone; Traditional Chinese medicine 　　 　　异位妊娠是妇科常见的急腹症之一,是孕妇孕早期死亡的主要原因,占所有妊娠的1%～2%[1]。近年来因人工流产、药物流产及盆腔炎的增加导致了异位妊娠的发病率不断上升,且趋于年轻化,未生育者明显增加[2];同时由于现代诊断技术如阴道B超、血β-HCG检测的提高及妇产科医师的警觉,使80%的异位妊娠在未破裂前被诊断[3],因此保留患者生育功能的治疗方法显得更加重要。如何提高药物治疗的成功率、增加再次宫腔妊娠率及减少副反应,现将我院用药