Ca_2722b_信号对肝癌细胞乙酰肝素酶(HPA)表达的影响.pdf

Ca_2722b_信号对肝癌细胞乙酰肝素酶(HPA)表达的影响.pdf

英文摘要 therewereno degradedsignificantlyfP0.05),But supematant the was differencebetweentheseand controlwhich significant andit 1 culture 1)in 0-i0.012)in (0,930土0.03cytoplasmwas(0.6 thesame wereno time,there significant supernatant.At di行erencebetweentheseandatadoseof SNAP 2009mol/L which andit was was(0.957土0.023)incytoplasm 1 r0.603+0.0 culture Wasthusclearthat 4)in supematant.It SNAP inhabitedthe effectofTGonHPA significantly inducing and therewasno secretion,but proteinexpression significantly onHPA innormalcell effect expression inhabiting protein withoutTG onthe Conelusions:1IntracellutarCa2+havenoeffect ofHPAonthelevelof it expression mRNA,whilesignificantly HPA andsecretionin inducesthe expression hepatoma protein 1cellonthelevelof carcinomaSMMC-772 protein. Ca2+ 2 inducerofintracellular Thapsigargin(TG),an stores enhancesthe

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