保留下颌骨与牙列舌癌根治术预后情况调查分析.docVIP

保留下颌骨与牙列的舌癌根治术预后情况调查分析 　　【摘要】 目的：对保留下颌骨与牙列的舌癌根治术在患者预后中的影响进行调查分析。方法：选取2010年1月-2015年1月本院口腔科接收并应用手术进行治疗的舌癌患者50例作为研究对象，将其分为观察组（保留下颌骨与牙列）与对照组（矩形切除下颌骨），每组25例，对患者预后进行分析。结果：观察组术后左右面型、咬合关系与术前一致，对照组术后面型出现了明显的塌陷现象，咬合缺失，且观察组患者生存质量明显高于对照组，组间比较差异均有统计学意义（P0.05）。结论：在舌癌患者的治疗中，临床上应该合理选择手术适应证，尽量应用保留下颌骨与牙列的舌癌根治术进行治疗，以保证临床疗效，提高患者生存质量。 　　【关键词】 舌癌根治术； 下颌骨； 牙列； 预后 　　【Abstract】 Objective：To research and analyze the influence of radical operation of lingual cancer without excision of mandible and dentition on patients after prognosis.Method：50 patients with tongue cancer admitted in our department of stomatology and received operation from January 2010 to January 2015 were chosen as research objects.They were divided into the observation group（with mandible and dentition retained） and the control group（removal of mandible in shape of rectangle），25 cases in each group，and the condition of prognosis of two groups were observed and analyzed.Result：In the observation group，both left and right facial contour and occluding relationship after operation were consistent with those before operation.However，in the control group，facial contour showed an apparent collapse occlusal loss.Quality of life in observation group was significantly higher than that in the control group，the difference between two groups was statistically significant（P0.05）. Conclusion：During treatment of tongue cancer，appropriate operative indications especially radical nephrectomy which retains mandible and dentition should be chosen so as to ensure clinical efficiency and improve life quantity of the patients. 　　【Key words】 Radical operation of lingual cancer； Mandible； Dentition； Prognosis 　　First-author’s address：Yuebei People’s Hospital of Shaoguan City，Shaoguan 512026，China 　　doi：10.3969/j.issn.1674-4985.2016.15.011 　　在口腔科，舌癌是一种比较常见的恶性肿瘤，在传统治疗中，常用的方法是舌颌颈联合根治术，改造手术方法虽然疗效较为理想，但需要切除较多的组织，对患者机体功能造成极大的破坏，严重影响着患者的生存质量[1-2]。近年来，肿瘤生物学、局部解剖术不断发展进步，保留下颌骨与牙列的舌癌根治术逐渐被应用到舌癌的治疗中，这种手术方法能够有效改善患者预后，提高患者生活质量[3-4]。为了进一步研究保留下颌骨与牙列的舌癌根治术