观察性健康医疗数据科学与信息学-OHDSI.PDF

Observational Health Data Sciences and Informatics (OHDSI) 观察性健康医疗数据 科学与信息学 George Hripcsak, MD, MS Biomedical Informacs, Columbia University Medical Informacs Services, NewYork-Presbyterian Observaonal Health Data Sciences and Informacs (OHDSI, as “Odyssey”) Mission: To improve health by empowering a community to collaboravely generate the evidence that promotes beer health decisions and beer care 使命：通过经过授权的团队合作，产生 科研证据来促进更好的健康决策和更好 的健康保健，改善健康状况 hp://ohdsi.org OHDSI’s global research community OHDSI遍布全球的合作团队 •  200 collaborators •  a billion records •  200 合作团队 •  10亿条数据记录 •  25 countries •  400 million paents •  25个国家 •  4亿病人数据 Broad experse 广泛的领域交叉 •  Stascs 统计学 •  Epidemiology流行病学 •  Informacs信息学 •  Soware engineering软件工程 •  Clinical medicine临床医学 Current problems in research 当前研究遇到的问题 Most research quesons have never been studied 大多数研究问题从未被研究过 All health outcomes of interest 所有感兴趣的健康结果 物 药 有 所 s g u r d l l A Unreliable evidence: inconsistent answers for the same queson 不可靠的证据：同一问题的答案不一致 August 2010: In the UK General Pracce Research Database, oral bisphosphonates are not Sept2010: In the UK General associated with esophageal cancer Pracce Research Database, oral 2010年8月：在英国全科医学研 bisphosphonates are associated 究数据库中，口服双膦酸盐与食 with esophageal cancer 管癌无关 2010年9月：在英国全科医学研