尼尔雌醇联合米索前列醇用于绝经后妇女取IUD前临床疗效观察.docVIP

尼尔雌醇联合米索前列醇用于绝经后妇女取IUD前临床疗效观察 　　[摘要] 目的 探讨尼尔雌醇联合米索前列醇用于绝经后女性IUD取出前的临床疗效。方法 选择绝经后女性宫内节育器取出前患者64例,随机将患者分为观察组和对照组,每组32例。两组患者在进行宫内节育器取出术前均给予顿服尼尔雌醇;观察组则在此基础上术前阴道放置米索前列醇。对两组患者宫颈软化程度及药物不良反应等指标进行对比分析。结果 与对照组相比,观察组充分软化的比率明显提高,而软化的比率明显降低,差别均具有统计学意义(P0.05)。且与对照组相比,观察组发生恶心、呕吐的比率明显降低,差别具有统计学意义(P0.05)。讨论 尼尔雌醇与米索前列醇联合应用于绝经后女性宫内节育器取出术前疗效确切,毒副作用小,是绝经后女性宫内节育器取出术的理想治疗方法。 　　[关键词] 尼尔雌醇;米索前列醇;宫内节育器 　　[中图分类号] R713.9[文献标识码] A[文章编号] 1673-9701(2010)10-141-02 　　 　　Clinical Observation of Nilestriol Combined Misoprostol for Post- menopausal Women before Remove the IUD 　　WANG Danying 　　Guangxi Hechi City Jinchengjiang Area of Family Planning Guidance Station,Hechi 547000,China 　　 　　[Abstract] Objective To probe into the clinical observation of nilestriol combined Misoprostol for post-menopausal women before remove the IUD. Methods Choice in postmenopausal women with IUD removed before the 64 patients randomly were divided into observation group and control group 32 cases. Two groups of patients with prior surgery during IUD removal for Gordon served Nylestriol. The observation group was on this basis in the preoperative vaginal misoprostol. In two groups of patients with cervical softening of the extent and indicators of adverse drug reactions were analyzed. Results Compared with control group, the ratio of the observation group to fully softened markedly improved, while the rate of softening significantly lower, there were significant differences (P0.05). At the same time, Compared with control group, observer Group nausea and vomiting rate significantly lower, there were also significant differences (P0.05). Conclusion Nilestriol and misoprostol used in combination therapy in postmenopausal women with IUD removal preoperative process, its curative effect and toxic side effects are post-menopausal women, IUD removal surgery for an ideal method of treatment. 　　[Key words] Nilestriol;Misoprostol;IUD 　　宫内节育器(IUD)是一种可以追溯到古代的非永久性避孕方法,但仅在本世纪才发展成为有效的避孕工具,并在世界范围内得以广泛应用[1]。女性进入绝经期后,由于卵巢功能衰退