尿培养菌落计数不达标原因分析.docVIP

尿培养菌落计数不达标原因分析 　　[摘要] 目的 分析尿培养菌落计数不达标的常见原因，提高尿细菌学检测结果准确性。方法 方便选取该院2015年6月―2017年6月收治的100例尿培养菌落不达标患者作为研究对象，回顾性分析所有患者临床资料。结果 该次不达标标本病原菌最为多见的是G-杆菌，其中最常见是肠杆菌科中的大肠埃希菌。100例患者中82例采用抗生素治疗有效或者存在尿路感染症状由于菌落计数未达标误判属于尿路感染阴性，其中提前应用抗生素者67例（81.7%），治疗有效33例（49.3%）。尿路感染症状患者尿沉渣涂片镜检发现WBC74例（74.0%）明显高于未发现WBC患者（8.0%），尿培养配合尿沉渣WBC阳性诊断符合率（90.2%）、阴性诊断符合率（55.6%）明显高于单纯尿培养诊断0.0%、18.0%。结论 尿培养菌落计数不达标的原因较多，单纯尿培养很难准确诊断提前使用抗生素患者尿路感染情况，配合尿沉渣涂片可减少误诊率。 　　[关键词] 尿培养；菌落计数不达标；原因分析 　　[中图分类号] R446 [文献标识码] A [文章编号] 1674-0742（2017）10（b）-0069-03 　　[Abstract] Objective This paper tries to analyze the common causes of colony count in urine culture so as to improve the accuracy of urinary bacteriology test. Methods 100 cases of non standard urine culture colonies from June 2015 to June 2017 were selected as the subjects， and the clinical data of all the patients were analyzed retrospectively. Results The most common pathogen of this substandard specimen was G-bacillus， the most common of which was Escherichia coli in enterobacteriaceae. In 100 patients， 82 cases with effective antibiotic treatment or urinary tract infection symptoms due to substandard colony count belonged to negative urinary tract infection， 67 cases of advanced application of antibiotics （81.7%）， 33 cases were effective（49.3%）. WBC of 74 cases of patients with symptoms of urinary sediment smear of urinary tract infection（74.0%）， significantly higher than that of no finding of WBC（8.0%）， urine culture with urine WBC positive diagnostic rate was 90.2% and negative diagnostic rate was 55.6%， significantly higher than that of pure urine culture diagnosis of 0.0% and 18.0%. Conclusion There are many reasons of the colony count failure in urine culture. It is difficult to diagnose the urinary tract infection with antibiotics by simple urine culture， and the rate of misdiagnosis can be reduced by using urinary sediment smear. 　　[Key words] Urine culture； Colony count failure； Causes analysis 　　泌尿道感染是临床较为常见的一种感染性疾病，目前临床主要通过尿培养进行诊断，但是尿培养结果容易受到患者自身以及