慢性心力衰竭伴多重耐药菌感染临床观察.docVIP

慢性心力衰竭伴多重耐药菌感染临床观察 　　[摘要]目的探讨慢性心力衰竭（CHF）伴多重耐药菌感染的临床特点及与相关危险因素的关系。方法选取邯郸市中心医院进行治疗的CHF患者130例，按照是否出现多重耐药菌感染分为多重耐药组（MR组）和非多重耐药组（NMR组），采用药敏试验耐药率情况，检测标本病原菌分布，分析相关危险因素。结果76例CHF伴多重耐药菌感染患者中呼吸道感染有35例占4605%，尿路感染23例占3026%，肠道感染12例占1579%，口腔感染4例占526%，穿刺感染2例占263%；多因素Logistic回归分析显示，糖尿病史、留置尿管、机械通气、使用抗生素、免疫抑制剂以及NYHA分级为CHF伴多重耐药菌感染的危险因素；76例CHF伴多重耐药菌感染患者共检出91株病原菌，其中革兰阴性菌为63株占6923%，革兰阳性菌为25株占2747%，真菌3株占330%。 　　[关键词]慢性心力衰竭；多重耐药菌感染；危险因素 　　中图分类号：R5417文献标识码：A文章编号：1009_816X（2016）02_0101_03 　　doi：103969/jissn1009_816orrelation Research on Clinical Characteristics of Chronic Heart Failure with Multi_drug Resistant Infections and Related Risk Factors of Chronic Heart Failure Combined with Multi_drug Resistant Infections. ZHANG Jian_hua， LI Hui， ZHAO Hui_ying， et al Handan Economic Development Zone Hospital， Hebei 056107， China 　　[Abstract] Objective To investigate the clinical characteristics of chronic heart failure with multiple drug_resistant infections and its relationship with risk factors Methods 130 patients of CHF were chosen from Handan Central Hospital They were divided into multidrug_resistant group （MR group） and non_multidrug_resistant group （NMR group） according to whether there had been multiple drug_resistant infections Antimicrobial susceptibility test was conducted to detect the pathogens distribution of samples by drug resistance rate， and relevant risk factors were analyzed Results Out of 76 cases， there were 35 cases of CHF with multi_drug_resistant infections had respiratory tract infection which accounted for 460%， 23 urinary tract infection cases （3026% ）， 12 intestinal infection cases （1579%）， 4 oral infections cases （526%）， and 2 puncture infection cases （263%）； multivariate logistic regression analysis showed that diabetes mellitus， indwelling catheter， mechanical ventilation， use of antibiotics， immunosuppressant and NYHA class were risk factors of CHF with multi_drug resistant infections； A total of 91 pathogenic strains were detected from the 76 cases