急性胰腺炎采用奥曲肽联合前列地尔治疗临床疗效观察.docVIP

急性胰腺炎采用奥曲肽联合前列地尔治疗临床疗效观察 　　摘要： 目的：探讨分析在急性胰腺炎的临床治疗中应用奥曲肽联合前列地尔的实际疗效以及其临床安全性。方法：选取我院2009年3月1日-2013年3月1日共收治的98例急性胰腺炎患者作为研究对象，按照随机原则将其分为对照组和观察组。对照组共47例患者，利用奥曲肽进行治疗；观察组51例患者，利用奥曲肽联合前列地尔进行治疗，回顾性分析其一般临床资料以及治疗过程，比较分析两种治疗方法的实际临床效果以及不良反应发生率。实验结果均使用SPSS18.0软件进行统计和分析。结果：两组患者在治疗1疗程后，对照组总有效率为70.2%，观察组总有效率为88.2%，两者差异比较具有统计学意义（P0.05）。安全性方面，对照组和观察组均无明显不良反应发生。其中，仅对照组出现3例休克患者以及1例肺炎患者。结论：奥曲肽联合前列地尔治疗急性胰腺炎能够取得较为满意的临床效果，不良反应发生率低，值得在临床上进一步研究并加以推广。 　　关键词：急性胰腺炎；奥曲肽；前列地尔；临床治疗The Clinical efficacy Of Octreotide alprostadil treatment of acute pancreatitis 　　Zhang Kunfeng，zheng Xiangdong，li Fan，yan Huaixiang （Baoan District， Shenzhen ，Songgang Peoples Hospital ，Lang xia， Community Health Service Center 　　Abstract：Objective： To investigate the efficacy analysis of the actual application of octreotide alprostadil in clinical treatment of acute pancreatitis and its clinical safety. Methods： Our hospital March 1， 2009 March 1， 2013 JCP treated 98 cases of acute pancreatitis patients as research subjects， according to the randomly divided into a control group and observation group. Control group of 47 patients， the use of octreotide treatment； observation group of 51 patients， the use of octreotide alprostadil treatment， a retrospective analysis of the clinical data and the treatment process， the actual comparative analysis of the clinical effects of the two treatment methods and poor The reaction rate. Experimental results are obtained using SPSS18.0 software for statistical analysis. Results： The two groups of patients after a course of treatment， the control group， the total effective rate was 70.2%， total effective rate was 88.2%， the difference was statistically significance （P 0.05）. Security， control group and observation group had no significant adverse reactions. Among them， only three cases occurred in the control group and one case of pneumonia in patients with shock patients. Conclusion： octreotide alprostadil treatment of acute pancreatitis can be achieved satisfactory clinical resu