肾衰宁联合爱西特治疗慢性肾衰竭临床观察.docVIP

肾衰宁联合爱西特治疗慢性肾衰竭临床观察 　　doi：10.3969/j.issn.1007-614x.2014.11.67 　　摘 要 目的：探索肾衰宁联合爱西特治疗慢性肾衰竭的临床疗效。方法：选择90例慢性肾衰竭患者，随机分为两组，治疗组45例，对照组45例，对照组给予常规治疗方法，治疗组在常规治疗方法基础上联合应用肾衰宁和爱西特。结果：治疗组总有效率显著高于对照组（P0.01），差异显著；与治疗前相比，治疗组治疗后Ccr明显升高，Scr、BUN明显下降（P0.01）；对照组治疗后Ccr明显下降，Scr、BUN明显升高（P0.05）。结论：肾衰宁联合爱西特对中早期慢性肾衰竭患者能改善肾功能，延缓慢性肾衰竭进展，治疗慢性肾衰竭疗效显著。 　　关键词 肾衰宁 爱西特 慢性肾功能衰竭 　　Clinical observation of Shen Shuai Ning combined with Ai Xi Te in the treatment of chronic renal failure 　　Liu Lanfeng 　　The Hospital of Baicheng City，Jilin 137000 　　Abstract Objective：To explore the clinical effect of Shen Shuai Ning combined with Ai Xi Te in the treatment of chronic renal failure.Methods：90 patients with chronic renal failure were selected，they were randomly divided into the treatment group and the control group with 45 cases in each.The control group was given conventional treatment，the treatment group was given Shen Shuai Ning and Ai Xi Te on the basis of the control group.Results：The total effective rate of the treatment group was significantly higher than that of the control group（P0.01），the difference was significant；compared with before treatment，Ccr of the treatment group was increased significantly after treatment，Scr，BUN were decreased significantly（P0.01）；Ccr of the control group was decreased significantly after treatment，Scr，BUN were increased significantly（P0.05）.Conclusion：Shen Shuai Ning combined with Ai Xi Te in the treatment of patients with early chronic renal failure can improve renal function，delay the progression of chronic renal failure，and its effect for the treatment of chronic renal failure is significant. 　　Key words Key words Shen Shuai Ning；Ai Xi Te；Chronic renal failure 　　慢性肾衰竭（CRF）是一种常见的终末期肾病（ESRD），是各种慢性肾脏疾病发展到晚期所表现的一组临床综合征。我们采用肾衰宁联合爱西特治疗中早期CRF患者取得了一定的疗效，现报告如下。 　　资料与方法 　　2009年2月-2012年12月收治慢性肾衰竭非透析患者90例，所有病例的诊断标准和分期均参照全国原发性肾小球疾病分型与治疗及诊断标准专题座谈会拟定的“慢性肾功能衰竭诊断标准和分期”。门诊患者62例，住院患者28例。其中男47例，女43例，年龄17～78岁，平均43岁，血肌酐（Scr）136～707.2μmol/L。原发病为慢性肾小球肾炎31例，糖尿病肾病22例，慢性肾盂肾炎9例，高血压肾病9