无创呼吸机辅助通气治疗COPD致肺源性心脏病伴Ⅱ型呼吸衰竭患者临床研究.docVIP

无创呼吸机辅助通气治疗COPD致肺源性心脏病伴Ⅱ型呼吸衰竭患者临床研究 　　【摘要】 目的：探讨无创呼吸机辅助通气治疗慢性阻塞性肺疾病（COPD）致肺源性心脏病伴Ⅱ型呼吸衰竭的临床效果。方法：选取本院收治的COPD致肺源性心脏病伴Ⅱ型呼吸衰竭患者60例作为研究对象，利用随机数字表法将所有研究对象分为对照组和观察组，每组各30例。对照组患者采用常规治疗，观察组患者实施无创呼吸机辅助通气治疗，观察两组患者的治疗效果。结果：观察组呼吸困难、胸闷心悸、剧烈咳嗽缓解时间均明显短于对照组，差异均有统计学意义（P0.05）；观察组血氧饱和度（SaO2）、酸碱值（pH）、动脉血氧分压（PaO2）、二氧化碳分压（PaCO2）均明显优于对照组，差异均有统计学意义（P0.05）；两组患者治疗总有效率比较，差异有统计学意义（P0.05）。结论：无创呼吸机辅助通气治疗COPD致肺源性心脏病伴Ⅱ型呼吸衰竭患者的临床效果突出，值得推广。 　　【关键词】 无创呼吸机辅助通气； COPD； 肺源性心脏病； Ⅱ型呼吸衰竭 　　【Abstract】 Objective：To investigate the clinical effect of noninvasive ventilator assisted ventilation in the treatment of pulmonary heart disease with type Ⅱ respiratory failure caused by COPD.Method：60 patients with pulmonary heart disease associated of type Ⅱ respiratory failure in our hospital were selected as the research objects.According to the random number table method，they were divided into control group and observation group，30 cases in each group.The control group was treated with conventional treatment，the observation group was treated with noninvasive ventilation，the clinical effects of two groups were observed.Result：The breathing difficulties，chest tightness，heart palpitations，acute cough relief time of the observation group were significantly shorter than those in control group，the differences were statistically significant（P0.05）.The SaO2，pH，PaO2，PaCO2 of the observation group were significantly better than those in control group，the differences were statistically significant（P0.05）.Conclusion：Noninvasive ventilator assisted ventilation in the treatment of pulmonary heart disease with type Ⅱ respiratory failure caused by COPD obviously have clinical effect，it is worth of promoting. 　　【Key words】 Noninvasive ventilator assisted ventilation； COPD； Pulmonary heart disease； Type Ⅱ respiratory failure 　　First-author’s address：Shaoguan City First People’s Hospital，Shaoguan 512000，China 　　doi：10.3969/j.issn.1674-4985.2017.01.003 　　慢性阻塞性肺疾病（COPD）是一?N破坏性的肺部疾病，是以不完全可逆的气流受限为特征的疾病，气流受限通常呈进行性发展并与肺对有害颗粒或气体的异常炎症