热疗结合介入化疗栓塞术治疗中晚期肝癌临床效果分析.docVIP

热疗结合介入化疗栓塞术治疗中晚期肝癌临床效果分析 　　【摘要】 目的：研究热疗与介入化疗栓塞术联合治疗中晚期肝癌的临床效果。方法：选取笔者所在医院2008年6月-2012年2月收治的80例原发性中晚期肝癌患者作为研究对象，按照随机数字表法将其分为治疗组和对照组，每组40例。治疗组采用热疗联合介入化疗栓塞术进行治疗，对照组单纯采用常规介入化疗栓塞术进行治疗。化疗方案采用四药联用。观察比较两组患者的临床疗效、卡氏评分改善情况、疼痛缓解情况和随访期间生存率的差异。结果：经治疗后，治疗组的治疗总有效率75.0%（30/40）明显高于对照组的40.0%（16/40），卡氏评分总改善率80.0%（32/40）明显高于对照组的50.0%（20/40），疼痛缓解率85.0%（34/40）明显高于对照组的35.0%（14/40），差异均有统计学意义（P0.05），而治疗组的2年生存率60.0%明显高于对照组的25.0%，差异有统计学意义（字2=10.0256，P=0.0015）。结论：热疗联合介入化疗栓塞术治疗中晚期肝癌疗效优于单纯介入化疗栓塞术，是治疗中晚期肝癌有效的综合治疗方法，值得临床推广应用。 　　【关键词】 中晚期肝癌； 热疗； 介入化疗栓塞术 　　中图分类号 R657.3 文献标识码 A 文章编号 1674-6805（2015）17-0006-03 　　Clinical Effect Analysis of Hyperthermia Combined with Interventional Chemotherapy Embolization in the Treatment of Advanced Hepatocellular Carcinoma/LIU Zu-hua.//Chinese and Foreign Medical Research，2015，13（17）：6-8 　　【Abstract】 Objective：To study the clinical effect of hyperthermia combined with interventional chemotherapy embolization in the treatment of advanced hepatocellular carcinoma.Method：80 patients with primary advanced hepatocellular carcinoma admitted to our hospital from June 2008 to February 2012 were selected as research objects，they were divided into the treatment group and the control group according to the random number table method，40 cases in each group.The treatment group was given hyperthermia combined with interventional chemotherapy embolization.The control group only received routine interventional chemotherapy embolization，the four drugs combined with chemotherapy.The clinical efficacy，KPS improvement，pain relief and survival rate during follow-up of the two groups were observed and compared.Result：After treatment，the total effective rate of the treatment group was 75.0%（30/40），which was significantly higher than 40.0%（16/40） of the control group，the total improvement rate of KPS in the treatment group was 80.0%（32/40），which was significantly higher than 50.0%（20/40） in the control group，the pain relief rate of the treatment group was 85.0%（34/40），which was signi