肺癌诊断和监控治疗中血清肿瘤标记物联合动态检测应用.docVIP

肺癌诊断和监控治疗中血清肿瘤标记物联合动态检测应用 　　[摘要] 目的 探讨血清肿瘤标记物联合动态监测在肺癌诊断及监控治疗中的应用效果及价值。方法 方便选取2014年10月―2016年10月该院治疗的肺癌病人100例（观察组）及同期肺部良性病变者100例（对照组）为对象，检测评定两组CEA、NSE、SCC-Ag肿瘤标记物。 结果 观察组血清肿瘤标记物水平显著高于对照组[（6.45±3.10）vs（2.98±1.113）]、[（16.78±6.12）vs（1.06±0.24）]，[（25.40±8.13）vs（10.10±5.13）]，差异有统计学意义（P0.05）；观察组I+II期与III+IV期不同分期、分型、复发及转移肿瘤标记物水平差异有统计学意义（P0.05）。观察组联合检查阳性率明显高于单项指标检出率（40 vs 8）（37 vs 8）（16 vs 8），差异有统计学意义（P0.05）。 结论 在肺癌诊断及监控治疗中，血清肿瘤标记物联合动态检测的应用价值高，值得推广应用。 　　[关键词] 肺癌；血清肿瘤标记物；动态监测；应用价值 　　[中图分类号] R734 [文献标识码] A [文章编号] 1674-0742（2017）01（c）-0056-03 　　Application of Serum Tumor Marker Combined with Dynamic Monitoring in the Diagnosis of Lung Cancer and Monitoring Treatment 　　WANG Qiong 　　Department of Tumor， Qujing First People’s Hospital， Qujing， Yunnan Province， 655000 China 　　[Abstract] Objective To discuss the application effect and value of serum tumor marker combined with dynamic monitoring in the diagnosis of lung cancer and monitoring treatment. Methods Convenient selection 100 cases of patients with lung cancer（the observation group） and 100 cases of patients with benign lung lesions （the control group） in our hospital from October 2014 to October 2016 were selected as the objects and the CEA， NSE and SCC-Ag tumor markers were tested and evaluated. Results The serum tumor marker level in the observation group was obviously higher than that in the control group[（6.45±3.10）vs（2.98±1.113）]，[（16.78±6.12）vs（1.06±0.24）]，[（25.40±8.13）vs（10.10±5.13）]， and the difference had statistical significance（P0.05）， and the differences in the staging， somatotype， recurrence and metastatic tumor markers had statistical significance（P0.05）， and the positive rate of combined examination in the observation group was obviously higher than that of single index [（40 vs 8），（37 vs 8），（16 vs 8）]， and the difference had statistical significance（P0.05）. Conclusion The application value of serum tumor marker combined with dynamic monitoring in the diagnosis of lung cancer and monitoring treatment i