肾动态显像评价2型糖尿病肾功能应用价值.docVIP

肾动态显像评价2型糖尿病肾功能应用价值 　　摘要：目的 探讨肾动态显像对糖尿病肾功能评估的应用价值， 　　关键词：肾动态显像；2型糖尿病；肾功能；糖尿病肾病 　　the application value of renal dynamic imaging in judgment of renal function in patients with type 2 diabetes mellitus 　　KONG Ning-ning ，ZUO Shu-yao ，WANG Deng-chun，WANG Zhi-qiang 　　（Department of Nuclear Medicine， The Affiliated Hospital of Qingdao University Medical College， Qingdao 266003， Shandong，China） 　　Abstract：Objective To evaluate renal dynamic imaging in judgment of renal functions in patients with type 2 diabetes mellitus so as to provide relevant basis for clinical diagnosis and treatment. Methods Sixty-six patients with type 2 diabetes mellitus classified by the urinary albumin excretion rate （UAER） into 3 grope ：grope 1， grope 2，grope 3. Thirty normal people without diabetes mellitus were included into control grope. Renal dynamic imaging were performed on all these cases as well as the serum creatinine （SCr） and blood erea nitrogen （BUN）had been done， the survey of the glomerular filtration rate （GFR），the renal function curve peak time （tb）， the half activity time （T1/2）， the 20 min residual rate （C20）， the SCr and BUN had been done； each grope of type 2 diabetes mellitus compared with control grope， just the grope of DM3 whose BUN and SCr were higher than the control grope ；every grope of type 2 diabetes mellitus the tb 、T1/2 were longer than the control grope， and the C20 was higher than control grope. Results The GFR of each grope of type 2 diabetes mellitus were 95.06±20.78，82.64±18.65，33.77±20.50（ml/min），were all statistically lower than the control grope which GFR was 111.95±15.24（ml/min）， （P0.05， P 0.01 and P0.01）. Conclusion Renal dynamic imaging is helpful for the early detection of the change of renal functions in patients with type 2 diabetes mellitus， judge the injury of the renal function and provide relevant basis for clinical prevention and diagnosis the Diabetic Nephropathy （DN）. 　　Key words：renal dynamic imaging； type 2 diabetes mellitus； renal f