胎儿期羊水污染对新生儿窒息影响.docVIP

胎儿期羊水污染对新生儿窒息影响 　　[摘要] 目的 分析新生儿窒息与胎儿羊水污染的关系。 方法 选择在我院进行分娩的新生儿618例为研究对象，比较羊水无污染以及不同污染程度胎儿胎心电图异常情况、新生儿发生窒息的情况。结果 羊水污染胎儿胎心监护异常率显著高于羊水正常的胎儿（P＜0.05），而羊水Ⅲ度污染的胎儿胎心监护异常率显著高于羊水Ⅰ度和Ⅱ度污染的胎儿（P＜0.01）。羊水污染新生儿窒息率显著高于无羊水污染的新生儿（P＜0.01）。羊水Ⅲ度污染的新生儿发生窒息率显著高于Ⅰ度和Ⅱ度污染的新生儿（P＜0.01）。结论 胎儿期羊水污染是胎儿宫内缺氧的早期表现，与新生儿窒息具有密切的关系。 　　[关键词] 新生儿窒息；羊水污染 　　[中图分类号] R722.12[文献标识码] B[文章编号] 1673-9701（2014）19-0147-02 　　 　　Influence of foetal period meconium-stained amniotic fluid for neonatal asphyxia 　　YUAN Jianhua 　　Department of Paediatrics， Guzhen People’s Hospital of Zhongshan City in Guangdong Province， Zhongshan 528421,China 　　[Abstract] Objective To discuss influence of foetal period meconium-stained amniotic fluid for neonatal asphyxia.Methods Selected 618 newborn were subjects. Abnormal fetal electrocardiogram rates andneonatal asphyxia of amniotic fluid 0 degree and Ⅰ to Ⅲ foetal period meconium-stained amniotic fluid were compared. Results Abnormal fetal electrocardiogram rates of cases with foetal period meconium-stained amniotic fluid were higher than those of cases with normal amniotic fluid（P＜0.05）， and abnormal fetal electrocardiogram rates of cases with Ⅲ degree foetal period meconium-stained amniotic fluid were higer than those of cases withⅠand Ⅱdegree foetal period meconium-stained amniotic fluid（P＜0.01）. Neonatal asphyxia rates of cases with foetal period meconium-stained amniotic fluid were higher than those of cases with normal amniotic fluid（P＜0.01）， and neonatal asphyxia rates of cases with Ⅲ degree foetal period meconium-stained amniotic fluid were higer than those of cases withⅠand Ⅱdegree foetal period meconium-stained amniotic fluid（P＜0.01）. Conclusion Fetal amniotic fluid pollution is early manifestation of fetal intrauterine hypoxia, and neonatal asphyxia has a close relationship. 　　[Key words] Neonatal asphyxia; Foetal period meconium-stained amniotic fluid 　　 　　新生儿窒息是指由于产前、产时或产后的各种病因，使胎儿缺氧而发生宫内窘迫或娩出过程中发生呼吸、循环障碍，导致生后1分钟内无自主呼吸或未能建立规律呼吸，以低氧血症、高碳酸血症和酸中毒为主要病理生理改变的疾病[1]。严重的