脑梗死抑郁发作因素及临床治疗研究.docVIP

脑梗死抑郁发作因素及临床治疗研究 　　摘 要：目的 分析脑梗死抑郁发作的危险因素，探讨合理的临床治疗措施。方法 选取我院2016年3月～2017年7月收治的200例脑梗死患者作为研究对象，分析脑梗死抑郁发作的危险因素；对所有患者进行汉密尔顿抑郁量表（HAMD）评分，比较治疗前与治疗后患者HAMD分值差异，同时给予受试者药物治疗，评价其临床治疗效果。结果 脑梗死患者抑郁的发作与患者性别、脑部病变部位、婚姻状况以及有无吸烟史有明显关系，差异具有统计学意义（P0.05）；与治疗前相比，治疗后患者HAMD评分明显降低，差异有统计学意义（P0.05）。结论 脑梗死抑郁的发作因素是多方面的，合理的药物治疗配合适当的心理治疗对于改善脑梗死患者的抑郁情况具有积极作用，值得临床大力推广。 　　关键词：脑梗死抑郁；发作因素；药物治疗；心理治疗 　　中图分类号：R749.1 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.04.069 　　文章编号：1006-1959（2018）04-0181-03 　　Abstract：Objective To analyze the risk factors of depressive episode in cerebral infarction and to explore the reasonable clinical treatment measures.Methods A total of 200 patients with cerebral infarction who were treated in our hospital from March 2016 to July 2017 were selected as study subjects to analyze the risk factors of depression in patients with cerebral infarction.The Hamilton Depression Rating Scale（HAMD）was scored on all patients.The differences of HAMD scores between pre-treatment and post-treatment HAMD scores were compared.At the same time，the subjects were given drug therapy to evaluate the clinical effect.Results The incidence of depression in patients with cerebral infarction was significantly related to the sex，location of brain lesion，marital status and smoking history，the difference was statistically significant（P0.05），compared with before treatment，HAMD score decreased significantly after treatment，the difference was statistically significant（P0.05）.Conclusion The onset of depression in patients with cerebral infarction is multifaceted.Rational drug treatment and appropriate psychological treatment measures have a positive effect on the improvement of depression in patients with cerebral infarction，and are worthy of clinical promotion. 　　Key words：Cerebral infarction depression；Attack factors；Drug therapy；Psychological treatment 　　脑梗死（cerebral infarction，CI）是指患者?X组织以及神经组织因缺血和缺氧而发生坏死或者功能性障碍，进而引起患者产生诸多神经系统功能紊乱的一种脑血管疾病[1，2]。脑梗死后抑郁症是目前临床较为常见的一种脑梗死并发症，它的发作具有较高的致残率和致死率，严重危害患者的身体健康，给