肝硬化腹水患者并发自发性细菌性腹膜炎危险因素分析.docVIP

肝硬化腹水患者并发自发性细菌性腹膜炎危险因素分析 　　[摘要] 目的 探究分析引起肝硬化腹水患者并发自发性细菌性腹膜炎（SBP）的相关危险原因，旨在为今后临床上治疗肝硬化腹水患者并发自发性细菌性腹膜炎提供参考和依据。方法 将2011年6月―2013年6月246例肝硬化腹水患者按有无SBP随机分为SBP组和非SBP组，SBP组41例，非SBP组205例。将两组的年龄、性别、发病原因、血小板、持续腹水时间、血清白蛋白、患者是否合并有糖尿病等方面进行比较分析，分析方法采用单变量或者多变量。 结果 单因素：SBP组患者的血清胆红素水平明显高于非SBP组，差异有统计学意义（P0.05）。多因素分析：血清白蛋白以及饮酒与自发性细菌性腹膜炎的发生有十分密切的关系（P0.05）。 结论 肝硬化腹水患者并发自发性细菌性腹膜炎的危险因素较多，其中饮酒和血清白蛋白是引发SBP发生的独立性高危因素，对此应加强相关方面的重视度。 　　[关键词] 肝硬化腹水；并发；自发性细菌性腹膜炎；危险因素；血清白蛋白；饮酒 　　[中图分类号] R57 [文献标识码] A [文章编号] 1674-0742（2015）03（a）-0051-03 　　Patients with liver Cirrhosis Complicated with Spontaneous Bacterial Peritonitis Risk Factors 　　HUANG Chujun 　　The First Peoples Hospital of Qujing Department of Gastroenterology，Qujing， Yunnan Province，655000，China 　　[Abstract] Objective To explore the analysis of patients with liver cirrhosis caused by spontaneous bacterial peritonitis（SBP） for reasons related risk， aims to provide reference and basis for the treatment of patients with liver cirrhosis complicated with spontaneous bacterial peritonitis clinical future. Methods June 2011 to June 2013 246 cases of liver cirrhosis patients were randomly divided according to whether the SBP SBP SBP group and non-group， 41 cases of SBP group， 205 cases of non-SBP group. The two groups of age， sex， etiology， platelets， continuous time ascites， serum albumin， whether patients with diabetes and other aspects of comparative analysis， analysis of univariate or multivariate. Results Univariate： serum bilirubin levels in patients SBP SBP group was significantly higher than the non-significant difference was statistically significant （P 0.05）. Multivariate analysis： serum albumin and drinking and the occurrence of spontaneous bacterial peritonitis have a very close relationship（P 0.05）. Conclusion Patients with liver cirrhosis complicated with spontaneous bacterial peritonitis more risk factors， including alcohol consumption and serum 　　自发性细菌性腹膜炎（SBP），就是无腹腔内器官穿孔和感染灶，比如脓肿、因急性感染而造成的腹水等。自发性细菌性腹膜炎具有较高的发生率和死亡率，属于肝硬化腹水患者的严