长效胰岛素联合口服降糖药治疗2型糖尿病疗效与安全性分析.docVIP

长效胰岛素联合口服降糖药治疗2型糖尿病疗效与安全性分析 　　[摘要] 目的 观察临床上针对2型糖尿病的患者，使用长效胰岛素（注射）、降糖药（口服）联合的方法治疗的效果和安全性。方法 2015年2月―2016年12月间选取该院2型糖尿病患者84例，将其分段随机化分2组，42例为一组。一组给予口服降糖药（对照组），另一组再使用长效胰岛素（观察组），对比2组各项血糖指标和发生的不良反应情况。 结果 观察组2型糖尿病患者的3项血糖数据较为平稳，不良反应数据是4.76%，优于对照组的各项情况（P0.05）。 结论 注射长效胰岛素和口服降糖药2者联合治疗2型糖尿病的患者，对于改善其血糖指标效果显著，且能够保证临床上较高的安全系数（不良反应发生概率较低）。 　　[关键词] 口服降糖药；长效胰岛素；2型糖尿病 　　[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062（2017）02（b）-0081-02 　　Analysis of Curative Effect and Safety of Long-acting Insulin and Oral Administration of Hypoglycemic Drugs in Treatment of Type 2 Diabetes 　　ZHANG Qian-jin 　　Endocrinology Department， Shuyang People’s Hospital， Suqian， Jiangsu Province， 223600 China 　　[Abstract] Objective To observe the curative effect and safety of long-acting insulin and oral administration of hypoglycemic drugs in treatment of type 2 diabetes. Methods 84 cases of patients with type 2 diabetes in our hospital from February 2015 to December 2016 were selected and randomly divided into two groups with 42 cases in each， the control group took the hypoglycemic drugs orally， and the observation group used the long-acting insulin， and the various blood glucose indexes and occurrence of adverse reactions were compared between the two groups. Results The three blood glucose data in patients with type 2 diabetes in the observation group and the adverse reaction data were steady and 4.76%， which were better than those in the control group（P0.05）. Conclusion The injection of long-acting insulin and oral administration of hypoglycemic drugs in treatment of type 2 diabetes can obviously improve the blood glucose index effect and ensure the higher safety coefficient in clinic （ the incidence rate of adverse reactions is low）. 　　[Key words] Oral administration of hypoglycemic drugs； Long-acting insulin； Type 2 diabetes 　　根据人们生活条件的改善，但随之而来的疾病――糖尿病的发生概率亦趋于上升阶段。糖尿病疾病主要与患者的环境因素、日常饮食习惯因素、遗传因素等息息相关。2型糖尿病是糖尿病疾病的其中一种类型，且较为常见[1]，其主要是因为患者机体当中的胰岛素作用不足，导致患者机体血液当中血糖的分解效果下降，最终因血糖浓度上升导致的症状。在临床上，通常针对2型糖尿病患者使