重复经颅磁刺激改善亚急性期缺血性脑卒中患者上肢运动功能随机对照研究.docVIP

重复经颅磁刺激改善亚急性期缺血性脑卒中患者上肢运动功能随机对照研究 　　[摘要] 目的 观察高频重复经颅磁刺激治疗亚急性期缺血性脑卒中患者上肢运动功能障碍的效果，为高频重复经颅磁刺激的使用提供依据。 方法 60例亚急性期缺血性脑卒中患者随机分为治疗组（n=30）和对照组（n=30）。两组常规治疗相同，治疗组给予重复经颅磁刺激治疗，刺激参数：频率10Hz，刺激时间3s，刺激个数30个，间歇时间35s，重复次数32次，治疗时间20min，刺激部位患侧大脑M1区。对照组不接受重复经颅磁刺激治疗。两患者于治疗前、治疗4周后接受Fugl-Meyer运动功能评定量表上肢部分（FMA）、改良Barthel指数（MBI）、WOLF运动功能测试量表（WMFT）评定。 结果 ?勺榛颊咭话阕柿媳冉喜钜煳尥臣蒲б庖澹?P0.05），具有可比性。治疗前两组患者的FMA（上肢部分）、MBI、WMFT评分分别为（治疗组vs对照组）（23.9±17.2）分 vs （22.3±14.8）分、（50.6±23.0）分 vs （46.8±18.2）分、（21.52±14.86）分 vs （20.76±17.21）分，差异无统计学意义。治疗4周后，两组患者的FMA（上肢部分）、MBI、WOLF评分分别为（治疗组vs对照组）（39.5±21.1）分 vs （29.0±19.5）分、（68.8±21.1）分 vs （57.8±16.9）分、（36.37±15.28）分 vs （28.09±16.43）分，差异均有统计学意义（P0.05）。 结论 高频（10HZ）重复经颅磁刺激能有效治疗亚急性期缺血性脑卒中患者的上肢功能障碍。 　　[关键词] 重复经颅磁刺激；脑卒中；亚急性期；上肢运动功能 　　[中图分类号] R743.3 [文献标识码] A [文章编号] 2095-0616（2017）07-187-04 　　Randomized controll study of repetitive transcranial magnetic stimulation in improvement of upper limb motor function of subacute ischemic stroke patients 　　YOU Guoqing LIANG Huiying YOU Guijuan HUANG Zhe 　　Department of Rehabilitation， Zhongshan Peoples Hospital，Zhongshan 528400，China 　　[Abstract] Objective To observe the effect of high frequency repetitive transcranial magnetic stimulation in treatement of upper limb motor function of subacute ischemic stroke patients，and to provide the basis for the use of high frequency repetitive transcranial magnetic stimulation. Methods 60 cases of subacute ischemic stroke patients were randomly divided into treatment group（n=30） and control group（n=30）.All the patients were treated with routine treatment.Patients in treatment group were treated with repetitive transcranial magnetic stimulation，and the stimulation parameters：Frequency was 10Hz，stimulation time was 3S，stimulation number was 30，intermittent time was 35S，Repeat time was 32，treatment time was 20 minutes，and the stimulation site was the brain M1 area.Patients in control group were not treated with repetitive transcranial magnetic stimulation.Fugl-Meyer motor function rating s