餐后高甘油三酯血症与糖尿病患者冠状动脉病变程度关系研究.docVIP

餐后高甘油三酯血症与糖尿病患者冠状动脉病变程度关系研究 　　[摘要] 目的 探讨餐后高甘油三酯（TG）血症与糖尿病患者的冠状动脉病变程度的关系。方法 选取该院2013年3月―2015年6月收治的180例2型糖尿病患者作为研究对象，按空腹TG及脂肪餐后TG水平将其分为餐后正常组、餐后增高组以及空腹高脂组3组。对3组的血糖与血脂指标进行测定，同时比较3组冠状动脉病变程度。结果 餐后正常组的空腹TG、4 h TG均明显低于餐后增高组与空腹增高组，餐后增高组又明显低于空腹高脂组（P0.01）；餐后正常组患者的双支病变、多支病变率均显著低于餐后增高组与空腹高脂组（P0.05）。 结论 2型糖尿病患者餐后高TG血症是引发冠状动脉病变的危险因素。 　　[关键词] 高甘油三酯血症；糖尿病；冠状动脉；病变程度 　　[中图分类号] R4 [文献标识码] A [文章编号] 1672-4062（2016）01（b）-0085-03 　　Study on the Relationship Between Postprandial Hypertriglyceridemia and the Extent of Coronary Artery Lesions in Patients with Diabetes Mellitus 　　WANG Gui-ping1，LIU Xiao-kun2，HAN Quan-le2，ZHANG Qi2 　　1.North China Institute of science and technology， University of science and technology，Tangshan，Hebei Province，063000 China；2.North China University of science and technology， Tangshan workers hospital，Tangshan， Hebei Province，063000 China 　　[Abstract] Objective To investigate the relationship between postprandial hypertriglyceridemia （TG） and the extent of coronary artery lesions in patients with diabetes mellitus. Methods 180 type 2 diabetic patients treated in our hospital from March 2013 to June 2015 were selected as the research object and were divided into three groups； the normal group after meal， postprandial increase group and fasting high fat group according to the TG level on empty stomach and postprandial fat TG level. Blood glucose and blood lipid indexes were measured in the 3 groups， and the extents of coronary artery lesions in the 3 groups were also compared. Results The postprandial TG and 4 hTG levels in the normal group were significantly lower than those in the postprandial increase group and fasting high fat group， and the postprandial TG and TG4h levels in the postprandial increase group were significantly lower than those in the fasting high fat group （P0.01）. The rate of double vessel disease and multiple lesions in the postprandial normal group were significantly lower than those in the postprandial increase group and fasting high