血液透析与持续不卧床腹膜透析患者恶性肿瘤发病率对比分析.docVIP

血液透析与持续不卧床腹膜透析患者恶性肿瘤发病率对比分析 　　[摘要] 目的：对比分析血液透析患者和持续不卧床腹膜透析患者恶性肿瘤发病率及临床特点。方法：选择2008年1月～2010年1月在我医院行血液透析治疗的患者70例，持续不卧床腹膜透析患者60例，对比分析恶性肿瘤的发生情况及临床特点。结果：70例血液透析患者中6例发生恶性肿瘤，发病率为8.5%。60例持续不卧床腹膜透析患者2例发生恶性肿瘤，发病率为3.3%。两组比较，有显著性差异（P＜0.01）。血液透析患者消化系统肿瘤发病率较高、持续不卧床腹膜透析患者肺癌发病率较血液透析患者高。结论：血液透析患者恶性肿瘤发病率明显高于腹膜透析患者。 　　[关键词] 血液透析；持续不卧床腹膜透析；恶性肿瘤 　　[中图分类号] R459.5[文献标识码]Ａ [文章编号]1673-7210（2010）11（a）-037-02 　　 　　Analysis on morbidity of m alignant tumor in the patients with hemodialysis and continuance ambulatory peritoneal dialysis 　　AN Kun 　　(Department of Nephrology, the First People′s Hospital of Jinzhou District in Dalian City, Dalian 116100, China) 　　[Abstract] Objective: To evaluate the incidence of m alignant tumors and its related factors, in patients including hemodialysis and continuance ambulatory peritoneal dialysis. Methods: We recruited 70 cases of patients with hemodialysis and 60 cases of patients with continuance ambulatory peritoneal dialysis in our hospital, then a cross sectional study to investigate the incidence and the clinical features of m alignant tumors. Results: Among the 70 hemodialysis patients, 6 case (8.5%) developed m alignant tumors, and among 60 continuance ambulatory peritoneal dialysis patients, 2 case (3.3%) developed m alignant tumors. There was a significant difference in two groups (P＜0.01). The incidence of digestive system tumors was quite high in hemodialysis patients, but lung caner was high in the patients with continuance ambulatory peritoneal dialysis.Conclusion: The incidence of m alignant tumors in hemodialysis patients is higher than that in continuance ambulatory peritoneal dialysis patients. 　　[Key words] Hemodialysis; Continuance ambulatory peritoneal dialysis; M alignant tumors 　　 　　随着血液透析和持续不卧床腹膜透析治疗技术的开展利用，终末期肾衰竭患者的生存期延长，生活质量不断提高，研究发现透析患者恶性肿瘤的发病率明显高于正常人群，影响透析患者的生存。本研究通过对本透析中心的透析患者恶性肿瘤发生情况进行调查，对血液透析和持续不卧床腹膜透析患者恶性肿瘤发生情况进行调查，探讨血液透析和持续不卧床腹膜透析患者的恶性肿瘤发生情况。 　　1 资料与方法 　　1.1 一般资料 　　收集我院2008年1月～2010年1月因终末期肾衰竭行透析治疗的患者130例，其中，血液透析