卵巢癌FIGO分期和C反应蛋白相关性分析.docVIP

卵巢癌FIGO分期和C反应蛋白相关性分析 　　【摘要】 目的：探讨卵巢癌病理分期与术前C反应蛋白值的相关性。方法：回顾性分析2008年1月-2012年6月手术的98例初治卵巢癌患者的病理资料及术前C反应蛋白值，并与同期手术的60例卵巢良性肿瘤进行比较分析。结果：早期组平均C反应蛋白值为（6.65±3.56）mg/L，晚期组为（43.70±23.85）mg/L，对照组为（3.13±0.55）mg/L，早期组与晚期组与对照组在C反应蛋白值上比较差异均有统计学意义（P0.05），晚期组C反应蛋白升高比例（75%）显著高于早期组（23.5%），比较差异有统计学意义（P0.05）。结论：C反应蛋白与卵巢癌病理分期密切相关，C反应蛋白对于卵巢肿瘤性质鉴别及病理分期预测有重要价值，从而对疾病预后有一定意义。 　　【关键词】 卵巢癌； 病理分期； C反应蛋白 　　中图分类号 R737 文献标识码 B 文章编号 1674-6805（2015）24-0018-02 　　Correlation between Staging of Ovarian Cancer with C-reactive Protein/CHENG Feng.//Chinese and Foreign Medical Research，2015，13（24）：18-19 　　【Abstract】 Objective：To investigate the relationship between staging of ovarian cancer with C-reactive protein.Method：The case of 98 ovarian cancer patients were selected from January 2008 to June 2012，and clinicopathological and C-reactive protein data were analyzed retrospectively.Result：The mean C-reactive protein was（6.65±3.56）mg/L in the early stage ovarian cancer group，（43.70±23.85）mg/L in the advanced stage ovarian cancer group，and （3.13±0.55）mg/L in the control group.Compared with the control group，there were significant differences in the data of C-reactive protein in patients with ovarian cancer.The same results were also observed between advanced groups and early groups（P0.05）.Conclusion：CRP is closely related to the pathologic staging of ovarian cancer，CRP is important for the identification of benign and malignant ovarian tumor diagnosis and the prediction of pathological staging，which have certain significance to the prognosis of ovarian carcinaoma. 　　【Key words】 Ovarian cancer； Pathological staging； C-reactive protein 　　First-author’s address：The Cancer Hospital of Zhejiang Province，Hangzhou 310022，China 　　doi：10.14033/ki.cfmr.2015.24.010 　　卵巢癌是女性常见恶性肿瘤，起病隐匿，多数患者就诊时已属晚期（Ⅲ～Ⅳ期），病死率高，居妇科恶性肿瘤首位。目前卵巢癌采用国际妇产科联盟（International Federation of Gynecology and Obstetrics，FIGO）病理分期，早期卵巢癌（Ⅰ～Ⅱ期）的5年生存率可达到91%[1]，晚期卵巢癌的5年生存率低，ⅢC期为32.5%，Ⅳ期为18.6%[2]。肿瘤分期是其最重要的预后因素，寻找可靠有效的指标来指导卵巢癌的早期诊断，让患者得到及时诊治，对提高生存率十