两种不同的方法检测敏感心肌肌钙蛋白Ⅰ的的结果比较.docVIP

两种不同的方法检测敏感心肌肌钙蛋白Ⅰ的的结果比较 　　【摘要】 目的:比较Beckman-Coulter Access免疫分析仪和强生VITROS-5600全自动干化学分析仪的两种敏感cTnI检测结果有无差异,了解两者之间的线性关系及相关程度。方法:收集本院急诊胸痛入院患者45例血清,分别用Beckman-Coulter Access免疫分析仪和强生VITROS-5600全自动干化学分析仪测定血清cTnI的浓度,比较两者之间的差异,并分析其相关性。结果:cTnI用这两种方法测得的结果差异无统计学意义 (P0.05),组存在显著相关性(P0.05)。结论:本实验室采用的这两种敏感cTnI的检测结果一致性较好。 　　【关键词】 心肌肌钙蛋白Ⅰ; Beckman-Coulter Access免疫分析仪; 强生VITROS-5600全自动干化学分析仪 　　Comparison of the Results of Sentive Cardiac Troponin I Detected by Two Different Detection Methods/SONG Jin-ping,MENG Xiao-hui,DAREN Bieke-sulitanbai.// Medical Innovation of China,2012,9(33):087-088 　　【Abstract 】 Objective:To comparise results of serum cardiac troponin I by Beckman-Coulter Access Immunoassay analyzer and Johnson VITROS-5600 fully automated dry chemistry analyzer,and exploring the differences as well as the linear relationship and correlation between the two.Method:45 serum samples were collected from patients presenting symptoms suggestive of acute myocardial infarction. The concentrations of serum cardiac troponin I were measured with Beckman-Coulter Access Immunoassay analyzer and Johnson VITROS-5600 fully automated dry chemistry analyzer. Data were processed by SPSS13.0 statistical analysis software.Result:Results of serum cardiac troponin I using the two methods showed no significant difference(P0.05), while analysis shows the significant relation between the two methods (P0.05).Conclusion:Results of sensitive cTnI in serum are detected by two instruments possessed high concordance. 　　【Key words】 Cardiac troponin Ⅰ; Beckman-Coulter Access Immunoassay analyzer; Johnson VITROS-5600 fully automated dry chemistry analyzer 　　First-author’s address:People Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830001, China 　　doi:10.3969/j.issn.1674-4985.2012.33.055 　　cTn因具有灵敏度高、特异性强、发病后出现较早且持续时间较长等特点,已成为目前诊断心肌损伤尤其是AMI的重要生物标志物[1]。与cTnT不同的是,一直以来市场上存在多种cTnI检测试剂,目前国内外使用较多的cTnI检测方法约20余种,各方法的分析性能差异很大。不同的检测方法是建立在不同技术平台上[2]。在这种情况下,检测结果之间可能会相差20~40倍,甚至100倍[3]。但是同一实验室同一检测项目,在两种不同的分析系统下得到的