抗原表位研究方法与口蹄疫病毒抗原表位研究进展.PDFVIP

微生物学通报 AUG 20, 2008, 35(8): 1302~1310 Microbiology © 2008 by Institute of Microbiology, CAS tongbao@ 专论与综述 抗原表位的研究方法及口蹄疫病毒 抗原表位的研究进展 张中旺 张永光* ( 730046) 摘 要: 本文综述了近几年来用于B 细胞表位及T 细胞表位研究的常用方法及其在口蹄疫病毒抗 原表位研究中的应用, 并介绍了口蹄疫病毒抗原表位的研究进展。 关键词: B 细胞表位, T 细胞表位, FMDV Approaches for Antigen Epitope Study and the Development of Antigen Epitopes of Foot-and-mouth Disease Virus * ZHANG Zhong-Wang ZHANG Yong-Guang (Key Laboratory of Animal Virology of Agriculture/State Key Laboratory of Veterinary Etiological Biology/Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046) Abstract: This paper reviews the common approaches for B cell epitopes and T cell epitopes study in recent years, and its application in foot-and-mouth disease virus (FMDV)’s antigen epitope study. The development of antigen epitopes of FMDV are also summarized. Keywords: B cell epitope, T cell epitope, FMDV (epitope) , ; , , ()()( , ); , B (antigenic determination) T; , , , , , , 5~7 , , 20 [1] T , , B, B 基金项目：(No. 20