基层医院抗菌药物的应用控制指标设定及干预对照的研究.docVIP

基层医院抗菌药物的应用控制指标设定及干预对照的研究 　　【摘要】目的了解抗菌药物应用控制指标设定前后, 本院抗菌药物临床使用情况。方法采取回顾性对比调查方法, 分析2012年指标控制前与2013年指标控制后, 本院抗菌药物使用率, 抗菌药物费用的变化；同时随机抽查2012年与2013年常见疾病1416例与1776例, 分析其抗菌药物使用合理性。结果抗菌药物应用控制指标设定后, 门诊抗菌药物处方比例由20.28%下降至18.31%；急诊抗菌药物处方比例由43.28%下降至38.77%；住院抗菌药物使用率分别为50.81%和55.30%；Ⅰ类切口手术抗菌药物使用率进一步降低, 分别为24.10%与21.50%；抗菌药物使用强度(DDDs)由38.20下降至37.10；抗菌药物占全院药品费用由20.73%下降至17.72%。结论抗菌药物应用控制指标设定有助于推进抗菌药物临床应用专项整治活动, 抗菌药物的规范性、合理性使用得到进一步提升。 　　【关键词】基层医院；抗菌药物应用控制指标；设定；干预对照 　　 　　Study on the control of the antimicrobial by indicators application setting and intervention in basic-level hospital FANG Yu-jian. Department of Pharmacy, Sixth Peoples Hospital of Nanhai District, Foshan 528248, China 　　【Abstract】Objective To compared clinical application of antibiotics before and after settingof application of antibiotics. Methods In order to know the change of the utilization ratio and the expense of antibiotics in our hospital, we analyzed the indicator in 2012(before control) and target in 2013(after control) with retrospective review; meanwhile, we took a random sample of 1416 cases and 1776 cases of common diseases in 2012 and in 2013 respectively and analyzed the reasonability of the usage of the antibiotics. Results After setting the guideposts of the application of antibiotics, the proportion of the use of the antibiotic prescription decline from 20.28% to 18.31% in outpatient department, from 43.28% to 38.77% in emergency, from 50.81% to 55.30% in inpatient department, from 24.1% to 21.5% in type I operative incision; the DDDs dropped from 38.2 to 37.1, the expense of the usage of the antibiotics accounting for the expense of all the drugs in our hospital come down from 20.73% to 17.72%. Conclusion Setting the guideposts of the application of antibiotics contributes to propelling the special program of antibiotics usage in clinic and promoting the antibiotics usage reasonably and normally. 　　【Key words】Basic-level hospital; Antimicrobial application control indicators; Setting; Inte