内科学课件32 SLE-8Y.pptx

Systemic Lupus Erythematosus; Systemic Lupus erythematosus ( SLE ) is a syndrome of unknown aetiology most commonly affecting young women. Virtually any organ of the body may be involved . Typically the course of the disease is a series of remissions and exacerbations. With good management, the ten years survival may be over 90%. ;Etiology and Pathogenesis of SLE;1. Genetic factor;;2. Environmental factors;Allergy. Does it induce lupus flare? No direct evidence. Infection. There has been continuing interest in the possibility that infectious agents might initiate or flare SLE