汶上县围孕期妇女叶酸利用程度调查及的的结果分析.docVIP

汶上县围孕期妇女叶酸利用程度调查及的的结果分析 　　【摘要】 目的：探讨汶上县围孕期妇女叶酸利用程度并且分析结果。方法：随机选取2011年8月-2014年8月3年内在山东省汶上县经过分娩的育龄期妇女862例作为研究对象。调查所有孕妇叶酸利用度、神经管畸形认知度、胎儿神经管畸形发生情况，并且测定孕妇血浆同型半胱氨酸（Hcy），分析叶酸利用程度与Hcy关系。结果：围孕期妇女年龄越大、受教育程度越高、家庭月收入越高、生产次数越多对叶酸的利用率及对神经管畸形的认知度越高，差异均有统计学意义（P0.05）。利用叶酸良好孕妇血浆Hcy明显少于利用叶酸差的孕妇，差异有统计学意义（P0.05）。利用叶酸差组胎儿神经管畸形发生率明显高于利用叶酸良好组，差异有统计学意义（P0.05）。神经管畸形组Hcy明显高于无神经管畸形组，差异有统计学意义（P0.05）。结论：围孕期妇女规律服用叶酸可以减少神经管畸形的发生，应根据不同人群采取相应的教育。 　　【关键词】 孕妇； 叶酸； 神经管畸形 　　中图分类号 R714.7 文献标识码 B 文章编号 1674-6805（2016）15-0078-03 　　【Abstract】 Objective：To study the usage of Folic Acid in perinatal pregnant women of Wenshang County and analyze the results.Method：862 women of childbearing age after delivery in Wenshang County from August 2011 to August 2014 were randomly selected as the research objects.The using degree of Folic Acid，neural tube defects，and the incidence of fetal neural tube defects were surveyed，the plasma homocysteine（Hcy） in pregnant women was measured and the relationship between the level of Folic Acid and Hcy was analyzed.Result：The higher the age，the education level，the family income and the number of production，the higher the use rate of Folic Acid and the recognition degree of the neural tube defects in pregnant women，the differences were statistically significant（P0.05）.The plasma Hcy of pregnant women with fine use of Folic Acid was significantly less than that of pregnant women with bad use of Folic Acid，the difference was statistically significant（P0.05）.The incidence of fetal neural tube defects in the bad use of Folic Acid group was higher than that in the fine use of Folic Acid group，the difference was statistically significant（P0.05）.The plasma Hcy of neural tube defects group was higher than that of non-neural tube defects group，the difference was statistically significant（P0.05）.Conclusion：Taking Folic Acid regularly can reduce the occurrence of neural tube defects，corresponding education shall be taken according to different crowds. 　　【Key words】 Pregnant women； Folic