全脑T灌注在评价颈内动脉系统对应脑组织慢性缺血中的应用价值.docVIP

全脑CT灌注在评价颈内动脉系统对应脑组织慢性缺血中的应用价值 北京大学首钢医院影像科，北京100144; 2.北京大学首钢医院神经内科，北京 100144 】A的探讨全脑CT灌注参数在评价颈内动脉系统血管狹窄相应脑 组织慢性缺血屮的应用价值。材料与方法回顾性分析57例颈内动脉系统主干 血管存在屮度或以上狭窄的动脉粥样硬化患者的CT灌注，包括脑血流量、脑血 容量、平均通过时间和达峰时间参数图，结合患者血管造影结果评价脑组织缺血 程度。结果57例患者屮度或以上狭窄的病变血管段共计115段，仅有7例颈 内动脉系统CTP无明显异常余50例见77个区域灌注异常，71个为梗死前期I 期，6个为梗死前期II期。其屮74个区域能找到对应责任血管82段，仅3个区 域未找及责任血管，且33段屮度或以上狭窄血管段对应供血区域未发现明确灌 注异常。结论当动脉粥样硬化患者颈内动脉系统主干血管发生屮度或以上狭窄 改变时，全脑CTP能够比较准确地反映相应脑组织慢性缺血的范围，评定其梗死 前期分期，为临床上精确诊治提供详实的影像学资料。 关键词】全脑CTP、颈内动脉系统、脑组织慢性缺血 The Whole-brain CT Perfusion in Valuing Chronic Cerebral Ischemia Patients With Hemadostenosis In Internal Carotid Artery System PAN Junl, ZHANG Binl, GAO Wei2, ZHANG Yuanfangl, WEN Qipingl, YAN Na2 Department of Radiology, Peking University Shougang Hospital, Beijing 100144, China Department of neurology, Peking University Shougang Hospital, Beijing 100144, China [Abstract] Subject: This study objective was to value the whole-brain CT perfusion (CTP) of chronic cerebral ischemia patients with hemadostenosis in internal carotid artery system, methods: 57 atherosclerosis patients with medium or more serious hemadostenosis occurring in main vessels of internal carotid artery system were studied. The degree of cerebral ischemia was estimated by angiography images and CTP data containing Cerebral Blood Flow (CBF), Cerebral Blood Volume (CBV), Mean Transit Time (MTT) and Time To Peak (TTP) in this retrospective study. Results: Post hoc exploration of this study revealed there were 115 segments with medium or more serious hemadostenosis in all subjects and 7 subjects had no evidently aberrant CTP. 77 regions had aberrant CTP in 50 subjects, and 71 regions were classified to pre-infarction period I stage besides 6 regions to pre-infarction period II stage. 74 regions could be found related 82 segments with hemadostenosis and 3 regions without. The regions with the rest 33 aberrant segments were found that there were no abnormal CTP. Conclusion: These results demonstrated the whole-brain CTP co