他克莫司软膏联合308 nm准分子激光治疗白癜风临床剖析.docVIP

他克莫司软膏联合308 nm准分子激光治疗白癜风临床剖析 　　[摘要] 目的 研究他克莫司软膏联合308 nm准分子激光治疗白癜风的临床应用及效果对比。方法 整群选择2014年2月―2016年2月该院收治的白癜风患者282例，选择患者双侧对称部位皮损作为研究对象，采用随机分组的方法分成观察组和对照组。对照组单独使用308 nm准分子激光的方法进行治疗，观察组使用他克莫司软膏联合308 nm准分子激光的方法进行治疗，治疗时间为3个月，对比两组治疗后的治疗效果，以及不良反应的发生机率。 结果 治疗3个月后，观察组的治疗总有效率为96.45%，高于对照组的80.14%，差异有统计学意义（P0.05）。结论 采用他克莫司软膏联合308 nm准分子激光的方法治疗白癜风，能够取得理想的临床疗效，不良反应的发生机率较少，具有较高的安全性。 　　[关键词] 他克莫司软膏；308 nm准分子激光；白癜风；临床观察 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2016）12（b）-0109-03 　　Clinical Analysis of Tacrolimus Ointment Combined with 308nm Excimer Laser in the Treatment of Vitiligo 　　XIAO Peng ，WANG Jing 　　The Fifth Hospital of Fujian Province University of TCM Affiliated（Sanming Second Hospital）Dermatology Department， Sanming， Fujian Province， 366000 China 　　[Abstract] Objective To compare the clinical application and effect of Tacrolimus Ointment combined with 302 nm excimer laser in the treatment of vitiligo. Methods Group selection from February 2014 to February 2016 admitted to the hospital 282 cases of patients with vitiligo lesions， choose bilateral and symmetrical parts of patients as the research object， divided into observation group and control group by random methods. The control group used alone 308 nm excimer laser the treatment method， the observation group used Tacrolimus Ointment 308 nm excimer laser treatment， treatment time was 3 months after treatment， compared two groups of treatment effect， and adverse reaction The incidence. Results After 3 months of treatment， the total effective rate of observation group was 96.45%， higher than 80.14% in the control group， the difference was statistically significant （P 0.05）. Conclusion The method of Tacrolimus Ointment 308nm excimer laser treatment of vitiligo， can obtain the ideal clinical curative effect， less adverse reaction i 　　ncidence， with high safety. 　　[Key words] Tacrolimus Ointment； 308 nm excimer laser； Vitiligo； Clinical observation 　　在临床上，以往使用他克莫司软膏等药物方法进行治疗，随着医疗技术的发展，开始应用308 nm准分子激光的方法进行治疗，但是单独使用该方