慢性脑血管功能不全临床诊治剖析.docVIP

慢性脑血管功能不全临床诊治剖析 　　doi：10.3969/j.issn.1007-614x.2014.11.57 　　摘 要 目的：探讨和分析慢性脑血管功能不全的临床诊断情况及治疗效果。方法：收治慢性脑血管功能不全患者120例，对所有患者的临床资料及影像学检查结果进行回顾性分析。结果：经颈部彩超检查后，管腔轻度狭窄45例（43.3%），中度狭窄52例（37.5%），重度狭窄23例（19.2%）；临床表现CCVI-Ⅰ型35例（29.2%），CCVI-Ⅱ型42例（35.0%），CCVI-Ⅲ型43例（35.8%）。经治疗后，观察组总有效率95.0%，明显优于对照组总有效率73.3%，两组比较差异有统计学意义（P0.05）。结论：对于慢性脑血管功能不全的患者，采用丹参川芎嗪注射液联合尼莫地平治疗效果显著，且安全可靠。 　　关键词 慢性脑血管功能不全 临床诊治 丹参川芎嗪 尼莫地平 　　Clinical analysis of diagnosis and treatment of chronic cerebrovascular insufficiency 　　Yin Xiuyun 　　The Peoples Hospital of Erdao District of Changchun City，Jilin 130031 　　Abstract Objective：To explore and analyze the clinical diagnosis and treatment of chronic cerebrovascular insufficiency.Methods：120 patients with chronic cerebrovascular insufficiency were selected，the clinical data and imaging findings of all patients were retrospectively analyzed.Results：Through the neck ultrasonography， 45 cases（43.3%） were mild stenosis of lumen，52 cases（37.5%） were moderate stenosis，23 cases（19.2%） were severe stenosis；Clinical manifestations：35 cases（29.2%） were CCVI-Ⅰtype，42 cases（35%） were CCVI-Ⅱtype，43 cases（35.8%） were CCVI-Ⅲ.After treatment，the total efficiency of 95% in the observation group was better than the total efficiency of 73.3% in the control group，the difference between the two groups had significant difference（P0.05）.Conclusion：For chronic cerebrovascular insufficiency patients，the effect of salviae miltiorrhizae and ligustrazine hydrochloride injection combined with nimodipine is remarkable，safe and reliable，and it is worthy of clinical promotion and application. 　　Key words Chronic cerebrovascular insufficiency；Clinical diagnosis and treatment；Salviae Miltiorrhizae and Ligustrazine Hydrochloride；Nimodipine 　　资料与方法 　　2011年1月-2013年1月收治慢性脑血管功能不全（CCVI）患者120例，男76例，女44例，年龄60～82岁，平均（65.7±13.1）岁。纳入标准：①年龄≥60岁；②伴有明显头痛、眩晕及头重等自觉症状，波动性消长；③患者眼底存在明显的动脉硬化性改变；④经颅脑CT检查为发现血管器质性病变。根据上述标准，将符合以上4项的患者视为慢性脑血管功能不全Ⅰ型，符合以上3项且经CT检测存在腔隙脑梗死者为Ⅱ型，符合以上3项且存在多方腔隙脑梗死者为Ⅲ型。将所有患者随机分为对照组和观察组，每组60