糖尿病视网膜病变眼底荧光血管造影剖析.docVIP

糖尿病视网膜病变眼底荧光血管造影剖析 　　【摘要】 目的 探讨糖尿病性视网膜病变(DR)各期的毛细血管无灌注区(NP区)易发部位及黄斑水肿发生情况。方法 通过对116例(209眼)DR患者进行眼底荧光血管造影(FFA)检查,发现NP区的分布特点及黄斑水肿特点。结果 116例(209眼)中有126眼存在NP区,发生率为60.29%,且NP区易发于中周部、其次为周边部、较少发生于后极部,发生率分别为82.54%、41.27%、16.67%。116例(209眼)中合并黄斑水肿79眼,发生率为37.80%,其中局限型占20.25%、弥漫型占51.90%、囊样型占20.25%、缺血型占7.59%。结论 视网膜中周部为NP区易发部位,黄斑水肿与病变程度有一定关系。 　　【关键词】 眼底荧光血管造影;糖尿病性视网膜病变;毛细血管无灌注区;黄斑水肿 　　 　　Analysis of fluorescence fundus angiography to diabetic retinopathy 　　 　　ZhAO Qing-xin, WANG Yan-yan, FENG Yu, et al. 　　Department of Ophthalmology, the Central Hospital of Xinxiang City, Henan Province, Xinxiang453000,China 　　 　　【Abstract】 Objective To study the susceptible position of capillary non-perfusion area (NP area) of diabetic retinopathy (DR) and the occurrence of macular edema.Methods To observe the 116 cases (209 eyes) DR with fundus fluorescein angiography (FFA), discovered the character of distribution of NP area and macular edema. Results In all cases,126 eyes exist NP area, incidence rate of 60.29%, and the most susceptible position of NP areas near the periphery with the incidence of 82.54%, followed by peripheral and less posterior pole of 41.27 % and 16.67%. 79 eyes with macular edema with the incidence rate 37.80%, which accounted for 20.25% of localized, 51.90% of diffuse type, 20.25% of cyst-like type, 7.59% of ischemic type. Conclusion The susceptible position of NP areas near the periphery, macular edema is certain correlated with the severity of DR. 　　【Key words】Fluorescence fundus angiography; Diabetic retinopathy; Capillary non-perfusion; Macular edema 　　随着人均寿命的延长及饮食结构的变化,糖尿病及其眼部并发症也呈逐渐增多的趋势。糖尿病性视网膜病变(diabetic retinopathy,DR)是糖尿病中最常见及最严重的并发症之一,仅以检眼镜检查结果为依据,对DR进行视网膜光凝治疗,已远远不能满足对DR患者的早期干预性治疗,通过眼底荧光血管造影(FFA)的结果分析,对进行DR各期的NP区易发部位、黄斑水肿分型及指导视网膜光凝治疗具有重要意义。现将河南省新乡市中心医院眼科2007年6月至2009年3月确诊为DR的116例(209眼)FFA检查结果进行分析,报告如下。 　　1 资料与方法 　　1.1 一般资料 2007年6月至2009年3月在本院确诊为DR并进行FFA检查的患者116例(209眼),其中男69例(121眼)占57.89%,女47例(88眼)占42.11%,年龄32～86岁,对合并有视网膜静脉栓塞和玻璃体积血等眼底病未列入统计。 　　1.2