低剂量胸部CT扫描技术研究-放射医学专业论文.docx

II II 中文摘要 低剂量胸部 CT 扫描技术研究 CTDI100，并计算出 CTDIW，根据螺距计算出 CTDIvol。结合第一步实验的 MTF 值、噪声 σ 计算 Q2 因子大小，选择 Q2 因子较大的扫描方案（120kV 50mA、120kV 60mA）对肺结节病人进行扫描，图像进行主观评价。比较两者的结节发现率。 结果 .常规条件下获得图像的空间分辨率高于低剂量条件。线对法目测值与 MTF 为 10%时对应的空间分辨率一致（t=0.18 P=0.8556）。低剂量条件下部分 MTF 曲线受噪声影响导致 MTF 值增大。 .与常规扫描条件相比低剂量扫描条件下（120kV 50mA、120kV 60mA）虽 然窗位为纵膈窗时纵膈区伪影与噪声有所增加（原因为纵膈区组织密度较肺区为 高且密度差较小，低剂量条件下不能很好的在图像上进行区分），但肺窗依然能 分辨肺结节以及周围解剖结构，并且两者的结节发现率无统计学差异。 结论 1.本研究验证了线对法目测值与 10%MTF 值的一致性，为主观性测量 CT 图 像的空间分辨率提供了客观依据。 2.通过实验对标准扫描条件以及低剂量扫描条件诊断准确率的统计学分析， 证明以 Q2 因子作为低剂量扫描方案的评价标准是可行的，为低剂量扫描评价提供 了一个依据，为解决了当前低剂量扫描条件差异较大的问题提供了一个可行的途 径。从而推进低剂量 CT 在临床上的使用，降低受检者的辐射剂量。 关键词: 低剂量胸部 CT；空间分辨率；MTF 法；线对法；噪声；Q2 因子 作 者：顾思毅 指导老师：孙 亮 副教授 III III Scan technology research of low-dose chest CT Abstract Scan technology research of low-dose chest CT Abstract Currently,CT examination’s clinical applications are more widely, protection issues of subjects have received increasing attention.However, reduce the radiation dose of CT examinations which will reduce the quality of CT images , increase the rate of misdiagnosis.It is necessary that reduce the radiation dose subjects, while ensuring the CT images to meet the requirements of clinical diagnosis, thereby promoting the rational use of CT.In the course of clinical practice, spatial resolution is a core indicator of CT image quality evaluation,it is crucial to obtain diagnostic information and correct diagnosis of diseases.The main methods of spatial resolution measurements are line pair method and MTF method,correlation analysis between the two methods has great significance for the routine quality control of CT. Objective This research was about the spatial resolution reflected in the image of CT through two different low dose scanning conditions,and the correlation between the two methods. Studied the possibility of Q2 factor as a evaluation standard for low-dose chest CT scan programs. Methods Using GE LightSpeed 16 CT scanned located midline CPT 528 module of Catphan 500 phantom.Sca