原发性肝癌中晚期患者经肝癌介入治疗后的效果及对肝功能的影响.docVIP

原发性肝癌中晚期患者经肝癌介入治疗后的效果及对肝功能的影响 ［摘要］目的探讨介入治疗对原发性肝癌中晚期患者的疗效及对肝功能的影 响。方法选择我院2012年2月~ 2014年2月间收治的50例原发性肝癌患 者为研究对象,采用肝癌介入治疗技术对其进行诊治，对比分析患者治疗后的效 果及对其肝脏功能的影响。结果介入治疗2次后患者的完全缓解率（58.00% ） 明显高于治疗1次后的完全缓解率（30.00% ），差异具有统计学意义（Pv0.05 ）。 治疗后第1天,患者的ALT和TBIL较治疗前明显升高，ALB则明显降低，考虑 与治疗相关的肝损伤有关，差异具有统计学意义（Pv0.05 ）。治疗后1周，ALT、 TBIL及ALB TBIL及ALB逐渐恢复至正常范围 较治疗前差异具有统计学意义 P0.05 ）。 术后1周复查AFP的结果显示，术后1周较治疗前有所降低，但差异不具有统 计学意义（P0.05 ）o表明介入治疗对患者的肝功能有明显改善效果。结论介 入治疗对原发性肝癌中晚期患者临床疗效显著，对患者肝功能改善明显，具有较 大的临床价值。 [关键词]原发性肝癌；中晚期肝癌；介入治疗；肝功能 [Abstract] Objective To investigate the efficacy and effect on liver function of interventional treatment for the patients with advaneed primary hepatocellular carcinoma. Methods From February 2012 to February 2014 ; 50 patients with primary hepatocellular carcinoma received interventional treatment in our hospital z and the efficacy and effect on liver function were observed. Results The complete remission rate after two treatments ( 58.00% ) was significantly higher than that after one treatme nt ( 30.00% ), the d iff ere nee was statistically sign ifica nt (P0.05 ). After first days of treatment, the patients ALT and TBIL were significantly higher than before treatment z while ALB was significantly lower z and the d iff ere nee was statistically sign ifica nt ( P0.05 ) . After 1 weeks of treatment, ALT , TBIL and ALB gradually recovered to the normal range , and the difference was statistically significant ( P0.05 ). After 1 week of operation , the results of AFP showed that there was a decrease in 1 week after surgery than before treatment z but the d if fere nee was not statistically sign ifica nt ( P0.05 ). The results indicated that the interventional treatment could improve the liver function effectively. Conclusion The interventional therapy is effective for patients with advaneed primary hepatocellular carcinoma , which can improve the liver function and has great clinical value. [Key words] Primary hepatocellular carcinoma ; Advaneed hepatocellular carci noma ; Inter