健脾消痞浸膏对脾虚动物胃运动及分泌影响的实验研究-中医内科学专业论文.docxVIP

中文摘要目的：观察健脾消痞浸膏对脾虚动物胃运动及分泌的影响。方法：用大黄水 中文摘要 目的：观察健脾消痞浸膏对脾虚动物胃运动及分泌的影响。方法：用大黄水 煎剂造脾虚动物模型，以比色法测定液体的胃排空，通过胃残留物重的测定来了 ／ 解固体的胃排空，用放射免疫法测定血浆胃动素，用滴定法了解胃分泌功能。f结 、 果：(1)脾虚动物胃排空液体和固体减少，血浆胃动素降低，胃分泌减少。(2) 健脾消痞浸膏组胃内液体残留率显著降低(PO．01)。(3)健脾消痞浸青中剂量 组胃内固体残留率降低(P(O．05)，高剂量组胃内圆体残留率显著降低(Po．01)。 (4)健脾滑痞浸膏中剂量组血浆胃动素升高(P0．05)，高剂量组血浆胃动素显 著升高(PO．01)。(5)健脾消瘩浸膏中剂量组总酸度、总酸排出量升高(PO．05)， 胃液量有升高趋势(PO．05)；高剂量组胃液量、总酸度、总酸排出量均显著升 、 f 高(Po．01)。，7结论：健脾消痞浸硎促进脾虚动物胃排空液体及固体，提高血浆 7 L 胃动素，促进胃液分泌。 关键词：健脾消痞浸膏、脾虚动物、胃排空v胃动素、胃分泌i ABSTRACTObjective：To ABSTRACT Objective：To observe the effects of Jian Pi Xiao Pi Jin Gao on stomach motion and secretion of animals with spleen deficiency．Methods：Animal model of spleen deficiency was set up by using Dahuang；the function of gastfic emptying liquid was assayed by recalls of chromometry；the function of gastric emptying solid Was observed by weighing remains in mouse stomach；motilin in plasma was measured by radioimmunoassay while the function of stomach secretion was assayed by means oftitration．Results：(1)Fewer gastric emptying liquid and solid as well as motilin in plasma and stomach secretion of animals with spleen deficiency were found．(2)The rate of residual liquid in the stomach Was significantly lower in the group of Jian Pi Xiao Pi Jin Crao qPO．or)．(3)The rate ofresidual solid in the stomach was lower in the middle dosage group ofJian Pi Xiao Pi Jin Gao(P0．05)，but significantly lower in the high dosage group(P0．01)．(4)Motilin in plasma was higher in the middle dosage group ofJian Pi Xiao Pi Jin Gao(PO．os)，but significantly higher in the high dosage group(P0．oi)．(5)The total acidity and the output of total acid became higher in the middle dosage group of Jian Pi Xiao Pi Jin Gao(PO．05)whereas the amount ofgastric juice in the same group had nO statistic significance(P0．05)．The amount of gastric juice，the total acidity and the output of total acid became significantly higher in the high dosage group fP0 01)Conclusion：Jian Pi Xiao Pi Jin Gao could not only improve the fu