慈利县原石门雄黄矿污染区地方性砷中毒流行病学调查.docxVIP

慈利县原石门雄黄矿污染区地方性碑中毒流行病学调查 湖南省慈利县疾病预防控制中心427200 摘要：目的探讨慈利县碑污染区暴露人群的病情程度和发病特点, 为疾病防治工作提供科学依据。方法依据《地方性砒中毒诊断标准》WS/ T211-2001,对碑污染区暴露人群进行碑中毒普查，同时进行流行病学调查。结 果 共调查892人，碑中毒患者325人，患病率36.43%,碑中毒患病率与年龄有 关，年龄越大，患病率越高(X2二85.89, PV0.05)；男性础中毒患病率为48.16%, 明显高于女性碑中毒患病率22.28% (X2二63.91, PV0.05) ?有碑采矿职业史的农 民工患病率为85.80%,明显高于本地农民患病率25.48% (X2=2.08, P0.05)。 临床表现主要为皮肤色素改变，掌跖过度角化等皮肤病变。结论雄黄矿污染区 三个村，地域广、人数多、病情重。必须采取综合防治措施，才能有效遏制病情 发展。 关键词：地方性碑中毒；皮肤色素改变；流行病学 Abstract： Objective： To study the symptomatic degree and disease character from persons exposed to arsenic in the endemic arsenism area of CiU county, to previde a data for con trolling en demic arsenic poisio ning. Methods： The reside nts overlivei ng in three villages of the polluted areas near an arsenic mine were taken arsenism general investigation, carry on the epidemiological investigation at the same time.According to A standard of diagnosis for endemic arsenism rsquo;rsquo; (WS / T211-2001) .Results： 892 residents were investigated, among them, 325 cases of arsenism were diag no sed, the prevalence rate was 36.43%.The arse nism pre vale nee rate connected with age, the older the age was, the higher the rate was(X2=85.89, P0.05) .The rate for male was 48.16%, it was higher than that for female 22.28% (X2=63.91, P0.05) .The rate for migrant worker of arsenic occupational history was 85.80%, it was higher than that residents 25.48% (X2=2.08, P0.05) .major clinic manifestation are skin pigmentation, as well as metavarpal bone overkeratosis.Conclusion： there are wide region, large number of people and serious symptomatic in three villages of the polluted areas near an arsenic mine.Only taking intergrative control measure can, we contain the worsening of the condition effectively. Key words： Endemic arsenic poisoning； Pigmentation； Epidemiolgy? 湖南省石门雄黄矿是一个有300多年历史的老矿，位于石门县西 北部，1950年在石门和慈利两县交界的地区建设起雄黄矿区，1956年该矿开始 利用低品位矿炼制砒霜，在采炼过程中，污染了矿区和周围的土壤和水源等环境, 造成工人和周围农民慢性神中毒，有关文献已做报道【1】。为摸清我县国太桥乡 石门原雄黄矿污染区地方性神中毒的分布和流行规律，2015年6月慈利县疾病 预防控制中心对国太桥乡雄黄矿