新生儿重症高胆红素血症临床危险因素探讨.docxVIP

新生儿重症高胆红素血症临床危险因素探讨 梁道喜邵秀敏 陈琼 陈晓琪 (广东省东莞市清溪医院儿科523660) 【摘要】目的 分析引起新生儿患重症高胆红素血症的临床危险因素。方法 自2012年5月至2013年5月来我院进行治疗的高胆红素血症新牛儿患者中随机 抽取108例，按患者患病轻重分为A组和B组，其中A组为重度高胆红素血症 患者，共50例，B组为轻度高胆红素血症患者，共58例。应用Logistic回归模 型对所选患者患病的原因进行分析。结果 导致新牛儿患高胆红素血症的常见原 因主要有感染、早产、母乳、溶血、窒息以及原因不明等，其中以感染最为常见。 根据Logistic回归分析，感染、早产以及原因不明在A组与B组的比较中差异具 有统计学意义。结论引起新牛儿患重症高胆红素血症的常见临床危险因素是感 染、早产以及原因不明，把握重症高胆红素血症的危险因素，对该病的预防和治 疗具有重要意义。 【关键词】新生儿 重症高胆红素血症 危险因素 【中图分类号】R722.1 【文献标识码】A 【文章编号】2095-1752 (2014) 06-0078-02 In vestigate the Clin ical Risk Factors of Neonatal In tensive Hyperbilirubi nemia [Abstract 】Objective:To research the clin ical risk factors of n eonatal in tensive hyperbilirubinemia.Methods:During the time of May 2012 to May 2013,108 neonatal hyperbilirubinemia patients were selected and divided into group A and group B according to the severity of illness.There are 50 patients in group A who are severe hyperbilirubinemia and the other 58 patients were in group B who are slight hyperbilirubinemia.Analysis the causes of the disease by Logistic model.Results:The comm on factors cased neon atal inten sive hyperbilirubi nemia are infection, premature birth, breastfeeding, hemolysis, suffocation and others,a nd the most com mon factor is infectio n.The factors of in fecti on, premature birth as well as other unexplained factors were statistically sign讦icance in the comparison of group A and group B based on the Logistic analysis.Conclusion:The main clinical risk factors of neon ata I inten sive hyperbilirubi nemia are infection, premature birth as well as other unexplained factors,it is important to grasp the risk factors of severe hyperbilirubinemia for the prevention and treatment of the disease. 【Keywords］ Newbor n Neonatal In tensive hyperbilirubi nemia risk factors 新生儿高胆红素血症是新生儿期常见的疾病之一，占新生儿住院的首位 由于大量胆红素在体内积聚，未结合胆红素存在一定毒性，可引起患而心、脑、 肾、肝等多种器官损害，严重破坏着患者的免疫系统，使得患者的免疫力下降［3］。 一般该病发病率高，危害大，严重威胁新生儿健康，影响到我国优生优育国策和 民族素质。故积极寻找高胆红素血症的发病病因及危险因素是在源头上控制高胆 红素血症的最好办法。本文为深入探究引起新生儿患重症高胆红素血症的临床危 险因素，自2012年5月至201