面向复杂脑白质神经纤维结构重建的算法研究-机械工程专业毕业论文.docxVIP

ABSTRACT Focused on the reconstruction of complex white matter nerve fibers this paper quantitatively compared various fourth-order tensor imaging methods based on higher-order tensor diffusion imaging and introduced new water diffusion model for multi-fiber crossing. The main contents are shown as follows: Regarding noise simulation this study determined the quantitative relationship between the Rician noise and signal-to-noise ratio (SNR). Combining with the recommended standard of SNR of magnetic resonance image (MRI) the simulating noise to be applied was limited to a practical range, which is more consistent to the actual condition. This method enables the simulation conditions more realistic, making simulation results more practical, and provides a reference for the simulation experiment of diffusion-weighted signal. Comprehensive and quantitative comparison was made between the imaging results of the positive and non-positive definite fourth-order tensor imaging. Taking stability and accuracy of the reconstruction method as evaluation criteria a quantitative research for the effects of the noise and the number of diffusion weighted gradient directions was made. The ability to detect IVOH of the two methods was also evaluated in the regions of single fiber and multi-fiber. The study results can provide advice in the choice of white matter fiber reconstruction methods. Using the 4th order tensor decomposition method, the fiber reconstruction of the DWI in humen brain has been made and its ability to show fiber crossing in different regions was also studied. In order to further study the effect of positive definite the positive property was applied to this imaging method, then the reconstruction effect of the positive and non-positive method was compared. For DWI signal simulation the Monte Carlo method was introduced to solve the simulation with multi-fiber, non-equal volume effect. Besides that this method can determine the quantitative relationship between s