慢性偏头痛患者静息态功能磁共振研究-神经病学专业毕业论文.docxVIP

万方数据 万方数据 目 录 中文摘要············································································································1 英文摘要············································································································3 英文缩写············································································································5 研究论文 慢性偏头痛患者静息态功能磁共振研究 前言············································································································6 材料与方法································································································7 结果··········································································································10 附图··········································································································11 附表··········································································································13 讨论··········································································································14 结论··········································································································17 参考文献··································································································18 综述 慢性偏头痛研究进展············································································23 致谢··················································································································29 个人简历··········································································································30 中 中 文 摘 要 PAGE 10万方数据 PAGE 10 万方数据 慢性偏头痛患者静息态功能磁共振研究 摘 要 目的：慢性偏头痛(chronic migraine, CM)是一类发作频繁、每月超过 15 天且病程超过 3 月的偏头痛，发病时经常伴有颅神经、胃肠道及自主 神经症状。以往诸多研究均证实偏头痛患者存在脑部结构、功能等异常， 但 只 有 少 部 分 研 究 对 慢 性 偏 头 痛 进 行 了 探 讨 。 静 息 态 功 能 磁 共 振 (resting-state functional magnetic resonance imaging, rs-fMRI)反映的是静息 状态下脑部的活动，这有助于理解慢性偏头痛的发病原理。本研究运用局 部一致性(regional homogeneity, ReHo)方法对慢性偏头痛患者与健康受试 者脑部自发活动的特征进行比较、分析。 方法：本研究招募了性别、年龄、受教育程度均匹配的慢