喉癌治疗后复发的临床因素分析及治疗.docxVIP

喉癌治疗后复发的临床因素分析及治疗 1?岳阳市广济医院耳鼻咽喉头颈外科 湖南岳阳414000； 2?岳阳市岳化医院耳 鼻咽喉头颈外科湖南岳阳414000 【摘要】目的：探讨喉癌治疗后复发的临床因素以及治疗方案。方法：分析 201例喉癌病患复发的临床因素，并对其中46例复发喉癌病患的资料进行分析。 结果：性别、年龄、吸烟、嗜酒、分型、甲状软骨受侵等对复发率的影响无统计 学意义(pgt;0.05),临床分期、N分期、T分期、手术切缘对复发率的影响具 有统计学意义(plt;0.05)； 201例喉癌病患中46例复发，复发率为22.89%,其 中21例喉局部复发，19例颈淋巴结转移，6例颈淋巴结转移并局部复发；随访 3年，21例喉局部复发中15例生存、3例死亡、3例失访，19例颈淋巴结转移 中16例生存、2例死亡、1例失访，6例颈淋巴结转移并局部复发中5例生存、 无死亡病例、1例失访。结论：喉癌治疗后复发与临床分期、N分期、T分期、 手术切缘有关；定期随访有利于确定早期有无复发现象；目前喉癌复发后治疗方 法主要以手术治疗为主。 【关键词】喉癌；复发；临床因素；治疗 [Abstract]objective： to study the laryngeal cancer recurrenee after treatment of clinical factors and treatment options.Methods： analysis of 201 cases of recurrent laryngeal patients clinical factors, and analyzed the data of 46 cases of recurrent laryngeal cancer patients.Results： gender, age, smoking, drinking and classification, the in flue nee of the thyroid cartilage by assault on the recurre nee rate is no statistical significance (p gt; 0.05), clinical stage, N stage, T staging, surgical cut edge effect on recurrence rate of statistically signifies nt (p lt; 0.05)； 46 cases in 201 cases of laryngeal cancer patients relapse, the recurrence rate was 22.89%, including 21 cases of laryngeal local recurrenee and 19 cases analysis, 6 cases was metastasis and local recurrenee； Followed for 3 years, 15 cases in 21 cases of laryngeal recurrent survival, 3 cases died, 3 cases were lost to follow-up, 19 cases was transferred in 16 cases of survival, 2 cases died, 1 case lost to follow-up, 6 cases was metastasis and local recurrence in 5 cases were survival, no deaths, 1 case lost to follow-up.Conclusion： the laryngeal cancer recurrenee after treatment with the clinical stage, N, T stage, stage surgery cut edge； Regular follow-up to determine whether early recurrence phenomenon； Laryngeal cancer recurrenee after treatment methods are mainly composed of surgical treatment. [Key words]throat； Recurrence； Clinical factors.treatment 喉癌是临床上常见的头颈部恶性肿瘤之一，约占据我国全身肿瘤 1%至2%,约占据头颈部肿瘤11%至22%[l]o喉癌治疗常采用以手术为