系统综述和Meta分析幻灯片.ppt

* Smallest, largest, significant etc…. Can anyone tell the acute illness of our patient? = MI (streptokinase for reducing risk of mortality post MI from thrombotic event) Now, based on this forest plot do we give an antithrombotic drug for reperfusion (in this case streptokinase) = YES 1 = The overall effect is represented by the diamond at the bottom (labelled ‘Total’) and represents the combined or pooled ratio. The ends of the diamond represent the 95% CI. Here we can see that treatment reduces mortality by 34% * * * * * * * * * * * * * * * * * * * * AMSTAR = A measurement tool to assess systematic reviews Shea?et al.?BMC Medical Research Methodology?2007 7:10uality of Systematic Reviews * * * 1 min them, 1 min feedback Title, abstract or final paragraph of the introduction should state the question. Our PICO: P = patients with ACL injury = yes (initial injury suggests not chronic condition but no info on age) I = Early ACL reconstruction = yes C = Delayed reconstruction = yes O = clinical and radiological = unclear So overall we happy to say yes? Tip = If cannot ascertain what the focused question is after reading these sections, search for another paper. * 1 min them, 1 min feedback Title, abstract or final paragraph of the introduction should state the question. Our PICO: P = patients with ACL injury = yes (initial injury suggests not chronic condition but no info on age) I = Early ACL reconstruction = yes C = Delayed reconstruction = yes O = clinical and radiological = unclear So overall we happy to say yes? Tip = If cannot ascertain what the focused question is after reading these sections, search for another paper. * 1 min them, 1 min feedback Title, abstract or final paragraph of the introduction should state the question. Our PICO: P = patients with ACL injury = yes (initial injury suggests not chronic condition but no info on age) I = Early ACL reconstruction = yes C = Delayed reconstruction = yes O = clinical and radiological = unclear So overall