欣可聆预防人流术后宫腔粘连的临床研究.docVIP

PAGE PAGE 1 欣可聆预防人流术后宫腔粘连的临床研究 　　[摘要]目的分析透明质酸钠凝胶在人工流产术后宫腔粘连中的预防应用及效果。方法选择在笔者所在医院行人工流产术患者500例，随机分为对照组和治疗组两组，各250例。对照组行常规人工流产术，实验组在人工流产术后宫腔内注医用透明质酸钠凝胶。两组术后均常规给予抗生素及益母草制剂服用。术后定期随访，观察两组术后有无粘连。结果治疗组术后宫腔粘连发生率明显低于对照组，差异有统计学意义（P0.05）。同一年龄段两组宫腔粘连发生情况比较，差异有统计学意义（P0.05）。结论人工流产术后宫腔内注入透明质酸钠凝胶具有减少宫腔粘连发生、不良反应少等优点，值得在临床推广应用。 　　[关键词]透明质酸钠凝胶；人工流产；宫腔粘连 　　[中图分类号]R169.4[文献标识码]B[文章编号]1673-9701（2013）07-0151-03 　　Preventionofhighconcentrationofmedicalsodiumhyaluronategelinthetreatmentofintrauterineadhesionsafterabortion 　　SHENBingqiu 　　FertilitySection，theMaternalandChildHealthHospitalofJiaxingCityinZhejiangProvince，Jiaxing314000，China 　　[Abstract]ObjectiveToanalyzeoftheapplicationandeffectsofhyaluronicacidinthepreventionofintrauterineadhesionsafterabortion.MethodsAtotalof500patientsundergoingabortiontechniqueoftheauthor’shospitalwererandomlydividedintotwogroupsofcontrolgroupandthetreatmentgroup，with250casesofeachgroup.Thecontrolgroupwastreatedwithconventionalartificialabortion，andtheexperimentalgroupwastreatedwithintrauterineinjectionofsodiumhyaluronateafterabortion.Twogroupswereroutinelygivenantibioticsandmotherwortpreparationsafteroperation.Twogroupswerefollowedupregularafteroperationsurgeryandtestedadhesions.ResultsIncidenceofintrauterineadhesionsafteroperationoftreatmentgroupweresignificantlylowerthanthoseinthecontrolgroup，andthedifferencewasstatisticallysignificant（P0.05）.Thedifferenceofthetwogroupsinthesameageintrauterineadhesionswasstatisticallysignificant（P0.05）.Comparedwiththecontrolgroup，menstruationafteroperationoftreatmentgroupwerebetter.Thedifferencewasstatisticallysignificant（P0.05）.ConclusionSodiumhyaluronategelinjectedintotheuterinecavityafteroperationabortionhastheadvantagesofreducingintrauterineadhesionsandfeweradversereactions，andworthyofclinicalapplication. 　　[Keywords]Sodiumhyaluronategel；Abortion；Intrauterineadhesions 　　人工流产术后宫腔粘连是指人工流产术中导致子宫内膜损伤，引起子宫肌壁的相互粘连。临床主要表现为月经量减少、闭经及周期性腹痛等。随着未婚先孕和生育前反复人工流产次数的增加，宫腔粘连的发生率也随之升高，人工流产术后宫腔粘连成为引起不孕不育的重要因素[1，2]。人工流产后，由于创伤的存在，如果不进