血管内介入与药物静脉溶栓治疗急性缺血性脑卒中的效果比较.docxVIP

血管内介入与药物静脉溶栓治疗急性缺血性脑卒中的效果比较 　　【摘要】目的：對比血管内介入与药物静脉溶栓治疗急性缺血性脑卒中的效果。方法：选取2018年 　　2月-2019年12月本院收治的88例急性缺血性脑卒中患者，按照随机数字表法分为观察组和对照组，每组44例。观察组给予血管内介入治疗，对照组给予药物静脉溶栓治疗，比较两组临床疗效、治疗前后血流变学指标、炎性因子变化。结果：观察组总有效率为95.45%，高于对照组的81.82%（p0.05）。两组治疗前血流变学指标比较，差异均无统计学意义（p0.05）;两组治疗后高切黏度、低切黏度、血浆黏度、红细胞比容指标水平均显著下降，且观察组改善均较对照组更显著（p0.05）。两组治疗前炎性因子水平比较，差异均无统计学意义（p0.05）;两组治疗后crp、il-6、tnf-α指标水平均显著下降，且观察组下降均较对照组更显著（p0.05）。结论：与药物静脉溶栓治疗相比，血管内介入治疗急性缺血性脑卒中可显著提高临床疗效，改善血流变学指标，降低机体炎症反应，促进神经功能恢复，建议在临床上推广。 　　【关键词】血管内介入静脉溶栓急性缺血性脑卒中 　　comparsioneffectofendovascularinterventionanddrugintravenousthrombolysisinpatientswithacuteischemicstroke/liufuxuancong，lijinzhao，zouzhiling，yuanhong，wengshiyan，pengxianhua，linianxia.//medicalinnovationofchina，2020，17（11）：00-008 　　[abstract]objective：tocompareandanalyzetheeffectsofendovascularinterventionanddrugintravenousthrombolysisinpatientswithacuteischemicstroke.method：atotalof88patientswithacuteischemicstroketreatedinourhospitalfromfebruary2018todecember2019wereselected，theyweredividedintotheobservationgroupandthecontrolgroupaccordingtotherandomnumbertable，44casesineachgroup.theobservationgroupwasgivenendovascularinterventiontherapy，andthecontrolgroupwasgivendrugintravenousthrombolysis.theclinicalefficacyoftwogroupswascompared，andthelevelsofhemorheologicalindicatorsandinflammatoryfactorsoftwogroupsbeforeandaftertreatmentwerecompared.result：thetotaleffectiverateoftheobservationgroupwas95.45%，significantlyhigherthan81.82%ofthecontrolgroup（p0.05）.therewerenosignificantdifferencesinhemorheologyparametersbetweentwogroupsbeforetreatment（p0.05）.thecutviscosity，plasmaviscosity，andhematocritindexlevelsoftwogroupsaftertreatmentdecreasedsignificantly，andthehemorheologyindexesoftheobservationgroupimprovedmoresignificantlythanthoseinthecontrolgroup（p0.05）.therewerenosignificantdifferencesinthelevelsofinflammatoryfactorsintwogroupsbeforetreatment（p0.05）.thelevelsofcrp，il-6，andtnf-αintwogroupsaftertreatmentdecreasedsignificantly，andthelevelsofinflammatoryfactorsinthe