VEGF在鼻咽癌中的表达及其与预后关系（临床医学范文）.docVIP

VEGF在鼻咽癌中的表达及其与预后关系（临床医学范文） 文档信息 ： 文档作为关于“医学心理学”中“耳鼻咽喉科学”的参考范文，为解决如何写好实用应用文、正确编写文案格式、内容素材摘取等相关工作提供支持。正文8347字，doc格式，可编辑。质优实惠，欢迎下载！ 目录 TOC \o 1-9 \h \z \u 目录 1 正文 2 文1：VEGF在鼻咽癌中的表达及其与预后关系 2 1 材料与方法 3 1.1 材料来源 3 1.2 组织芯片的制作 3 1.3 组织芯片的免疫组化染色 4 1.4 统计方法 4 2 结 果 4 2.2 188例鼻咽癌患者的总生存曲线 5 2.3 TNM分期对鼻咽癌患者生存曲线的影响 5 文2：VEGF在鼻咽癌中的表达及其与预后关系 5 1 材料与方法 7 1.1 材料来源 7 1.2 组织芯片的制作 7 1.3 组织芯片的免疫组化染色 7 1.4 统计方法 8 2 结 果 8 2.2 188例鼻咽癌患者的总生存曲线 8 2.3 TNM分期对鼻咽癌患者生存曲线的影响 8 2.4 VEGF表达对鼻咽癌患者生存曲线的影响 9 2.5 VEGF表达对不同临床分期鼻咽癌生存曲线的影响 9 3 讨 论 9 参考文摘引言： 11 原创性声明（模板） 12 文章致谢（模板） 12 正文 VEGF在鼻咽癌中的表达及其与预后关系（临床医学范文） 文1：VEGF在鼻咽癌中的表达及其与预后关系 The Expression of Vascular Endothelial Growth Factor in Nasopharyngeal Carcinoma and Its Relatiohip with Prognosis Abstract: ［Purpose］ To investigate the expression of vascular endothelial growth factor（VEGF） in nasopharyngeal carcinoma (NPC) and its relatiohip with prognosis of NPC. ［Methods］ The expression of VEGF in 200 cases of NPC with followed-up data from 1990 to 2002 was analyzed by high-throughput tissue microarray technology and immunohistochemistry. The relatiohip between expression of VEGF and clinical characteristics of the patients with NPC was analyzed with chi-square test. The survival rates between different tissues VEGF expressio in NPC were compared. ［Results］ The positive expression of VEGF in NPC was observed mainly in cytoplasm of tumor cells. And the expression of VEGF in NPC tissue positively correlated with the TNM stage, recurrence and distant metastasis(P＜0.05). The 5 year overall survival rates of patients with positive and negative expression of VEGF were 40.11% and 67.75% respectively. The survival rates of different groups were significantly different by log rank test（P＜0.01）. ［Conclusion］ The expression of VEGF in NPC tissue positively correlated with the TNM stage, recurrence and distant metastasis. High expression of VEGF in patients with NPC predicts poor prognos