药学英语药学英语 (31).pptVIP

Unit Eleven Drug Safety and Efficacy Part five When balancing NNT against NNH, it is important to weigh the magnitude of specific benefits and harms. For example, a drug that causes many more harms than benefits may be worth prescribing if those harms are minor (e.g., reversible, mild)and the benefits are major (e.g., preventing mortality or morbidity). In all cases, patient-oriented outcomes are best used. 当权衡NNT与NNH时，考虑具体的有利和有害程度是很重要的。 举例来说，如果伤害轻微(如，可逆的、轻度的)且益处巨大(如，减少死亡率或发病率)，即使一种药物引起的伤害多于好处，也仍然值得开具处方。 在所有情况下，以患者为中心的结果最值得使用。 Genetic profiling is increas