药学英语药学英语 (34).pptVIP

Unit Eleven Drug Safety and Efficacy Part three However, surrogate outcomes should ideally be proved to correlate with patient-oriented outcomes. There are many studies in which such correlation appeared reasonable but was not actually present. For example, treatment of certain postmenopausal [?m?n??pa?z?l] 更年期;绝经 women with estrogen [?estr?d??n] and progesterone [pr??d?est?ro?n] resulted in a more favorable lipid profile but failed to achieve the hypothesized [ha??pɑ?θ?sa?zd] 假定的corresponding reduction in MI or cardiac death. 然而替代结果理想情况下应该被证明与以患者为中心的结果相关