空腹C肽及餐后2hC肽与空腹C肽比值对初诊2型糖尿病患者血糖波动的影响.docVIP

·2418 · ]P Chinese General Practice 2015,Yol,8 N6.20 · 论 著 · 空腹 C 肽及餐后2 hC 肽与空腹 C 肽比值对初诊 2型糖尿病患者血糖波动的影响 蒋泽，史爱梅，戚文群，唐宝康 【摘要】 目的 探讨空腹 C 肽 (Co)、 餐后2hC 肽 (C?) 与空腹C 肽比值 (C?/Co) 与初诊2型糖尿病患者血 糖波动的关系。 方法 选取2012年4月—2014年3月于泰州市第三人民医院内分泌科住院治疗的初诊2型糖尿病患者 54例为研究对象。患者入院后测定Co、 食用标准100g 馒头餐后2hC 肽 (C?) 水平，佩戴动态葡萄糖监测系统进行动 态血糖监测72 h, 记录日间平均血糖 (MBG)、 日间平均血糖波动幅度 (MAGE)、 血糖标准差 (SDBG)、 最大血糖波 动幅度 (LAGE)。 分别比较Co≥1.1μg/L和1. 1μg/L、C?/Co≥3.0 和3.0患者上述指标水平的差异。结果 C 1.1μg/L患者MBG、MAGE、SDBG、LACE 高于Co≥1.1μg/L患者，差异有统计学意义 (P0.05)。C?/Co3.0 患 者MBG、MAGE、SDBG、LACE 高于C?/Co≥3.0患者，差异有统计学意义 (P0.05)。 结论 C。及 C2/C。均能影响 初诊2型糖尿病患者血糖波动， Co1.1μg/L 和 C?/C。3.0的患者血糖波动较大。 【关键词】 糖尿病，2型；血糖； C 肽 【中图分类号】 R587.1 【文献标识码】 A doi:10.3969/j. issn.1007-9572.2015.20.014 蒋泽，史爱梅，戚文群，等.空腹C 肽及餐后2 hC 肽与空腹C 肽比值对初诊2型糖尿病患者血糖波动的影响 [J]. 中国全科医学，2015,18(20):2418-2420. [] Jiang Z, Shi AM,Qi WQ,et al. Effects of fasting C -peptide and the ratio of C?/Co on the blood glucose fluctuation in newly diagnosed type 2 diabetic patients [J]. Chinese General Practice,2015,18(20):2418-2420. Effects of Fasting C- peptide and the Ratio of C?/Co on the Blood Glucose Fluctuation in Newly Diagnosed Type 2 Diabetic Patients JIANG Ze, SHI Ai-mei, Ql Wen -qun, et al. Department of Endocrinology, the Third Peoples Hospital of Taizhou, Taizhou 225300,China 【Abstract】 Objective To investigate the effects of fasting C- peptide(Co)and the ratio of C2/Co on the blood glucose fluctuation in newly diagnosed type 2 diabetic patients. Methods We enrolled 54 newly diagnosed type 2 diabetic patients who were admitted into the Department of Endocrinology of the Third Peoples Hospital of Taizhou in Jiangsu Province from April 2012 to March 2014. The Co,C2 after 100 g steamed bun intake,72 h dynamic blood glucose monitor by wearing dynamic blood glucose monitoring system,MBG, MAGE, SDBG and LAGE of the patients were tested. The above indicators were compared between the patients with Co≥1.1 μg/L and patients with Co1.1 μg/L and between patients with