尿微量清蛋白与糖尿病足的关系研究.docVIP

·2104 · · 短 篇 论 著 · 尿微量清蛋白与糖尿病足的关系研究 吕翠叶，瞿勇 【摘要】 目的 探讨尿微量清蛋白 (UMA) 与糖尿病足 (DF) 之间的关系。方法 选取我院2007-2010年内 分泌科住院糖尿病患者526例，其中UMA(+) 患者103 例 ，UMA(-) 患者423例。比较 UMA(+) 与 UMA ( 一 )患者DF 患病率； UMA(+) 非糖尿病足 (NDF) 患者与 UMA(-)NDF 患者随访1年，观察新发DF 病例数； 将 UMA(+)NDF 患者分为UMA200mg/L 患者与20mg/LUMA≤200 mg/L 患者，随访1年观察新发DF 病例数。 结果 UMA(+) 患者DF 患病率(33.98%)显著高于UMA(-) 患者(3 . 78%) (P0.01)。UMA(+)NDF 患 者68例， UMA(-)NDF 患者407例，随访1年，前者DF 发病率(35.29%)显著高于后者(9.58%) (P0.01)。 68例 UMA(+)NDF 患者中， UMA200 mg/L患者25例，20 mg/LUMA≤200 mg/L惠者43例，随访1年，前者 DF 发病率(56.00%)显著高于后者(23.26%) (P0.01)。 结论 UMA 与 DF 的发生有关，且UMA 水平越高， DF 发病率越高。故早期干预UMA 有助于预防 DF 的发生。 【关键词】 尿微量清蛋白；糖尿病足；糖尿病 【中图分类号】 R587.1 【文献标识码】 B 【文章编号】1007-9572(2012)06-2104-03 Correlation between Urinary Minimum Albumin and Diabetic Foot LV Cui -ye, QU Yong. Department of Endocrinology, the Second Peoples Hospital of Zhuzhou City, Zhuzhou 412005, China 【Abstract] Objective To explore the relationship between urine minimum albumin(UMA)and diabetic foot (DF). Methods 526 patients admitted to the department of endocrinology of our hospital were selected. Of all the patients, there were 103 UMA(+)patients and 423 UMA(-)patients. The incidence of DF between UMA (+)patients and UMA ( 一 )pa- tients was compared. UMA(+)non-diabetic foot(NDF) patients and UMA (-)NDF patients were followed up for one year to observe new DF cases. UMA(+)NDF patients were divided into UMA200 mg/L group and 20 mg/LUMA≤200 mg/L group, and then they were followed up for one year to observe new DF cases. Results DF incidence of UMA(+)patients (33.98%)was significantly higher than that of UMA (-)patients(3.78%)(P0.01).The 68 cases of UMA(+)NDF and 407 cases of UMA (-)NDF were followed up for one year,the incidence of DF in UMA(+)NDF patients(35.29%) was significantly higher than that in the UMA(-)NDF patients(9.58%)(P0.01).Among the 68 UMA(+)NDF pa- tients, 25 c